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63096-02-6

N-(tert-butoxycarbonyl)-L-leucine methyl ester

CAS: 63096-02-6

Molecular Formula: C12H23NO4

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63096-02-6 - Names and Identifiers

Name N-(tert-butoxycarbonyl)-L-leucine methyl ester
Synonyms Boc-Leu-OMe
BOC-LEU-OME
Boc-L-Leu-OMe
Boc-L-Leucine methyl
Methyl N-(tert-butoxycarbonyl)-L-leucinate
N-(tert-butoxycarbonyl)-L-leucine methyl ester
3-[(2-acetamido-3-phenyl-propanoyl)amino]benzoic acid
L-Leucine, N-[(1,1-diMethylethoxy)carbonyl]-, Methyl ester
(S)-Methyl 2-((tert-butoxycarbonyl)aMino)-4-Methylpentanoate
CAS 63096-02-6
InChI InChI=1/C12H23NO4/c1-8(2)7-9(10(14)16-6)13-11(15)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,13,15)/t9-/m0/s1

63096-02-6 - Physico-chemical Properties

Molecular FormulaC12H23NO4
Molar Mass245.32
Density0.991g/mLat 25°C(lit.)
Melting Point147-149℃
Boling Point205°C(lit.)
Flash Point113°C
Vapor Presure0.000278mmHg at 25°C
Storage ConditionSealed in dry,2-8°C
Refractive Indexn20/D 1.44(lit.)

63096-02-6 - Risk and Safety

WGK Germany3

63096-02-6 - Introduction

N-(tert-butoxycarbonyl)-L-leucine ester is an organic compound with the chemical formula C13H25NO4 and a molecular weight of 259.34g/mol.

Properties: N-(tert-butoxycarbonyl)-L-leucine methyl ester is a white crystalline solid, soluble in some organic solvents such as ether and dimethylformamide. It is an air-stable compound, but breaks down easily in light.

Purpose: N-(tert-butoxycarbonyl)-L-leucine methyl ester is an important amino protecting group, which is often used to protect or synthesize natural products with complex structures in biochemistry and organic synthesis. It can effectively protect the amino group of leucine and prevent unnecessary reaction with other reactants.

Preparation method: N-(tert-butoxycarbonyl)-L-leucine methyl ester is usually prepared by esterification of L-leucine with methanol, and tert-butoxycarbonyl (BOC) is added as an amino protecting group during the reaction.

safety information: N-(tert-butoxycarbonyl)-L-leucine methyl ester is a kind of laboratory reagent, the operation needs to follow the relevant safety procedures. It is irritating to the skin and eyes and may cause allergic reactions. Appropriate protective equipment should be worn during use to avoid inhalation of gas or dust, and to ensure that the laboratory has a good ventilation system. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-10 22:29:15
63096-02-6
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