68392-35-8
(E/Z)-4-Hydroxy Tamoxifen
CAS: 68392-35-8
Molecular Formula: C26H29NO2
68392-35-8 - Names and Identifiers
68392-35-8 - Physico-chemical Properties
| Molecular Formula | C26H29NO2 |
| Molar Mass | 387.51 |
| Density | 1.092 |
| Melting Point | 135-144°C |
| Boling Point | 514.4±50.0 °C(Predicted) |
| Solubility | methanol: soluble10mg/mL |
| Appearance | solution |
| Color | white to off-white |
| pKa | 9.38±0.15(Predicted) |
| Storage Condition | 2-8°C |
| Physical and Chemical Properties | Bioactive 4-Hydroxytamoxifen (Afimoxifene) is an active metabolite of tamoxifen and a selective estrogen receptor regulatory molecule, which is widely used in the treatment and chemotherapy of breast cancer. 4-HT activates targeted modification efficiency of intein-Cas9 mutants. |
| Use | Uses Afoxifene is the active metabolite of tamoxifen in the body, which can be used as an organic intermediate. |
68392-35-8 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R63 - Possible risk of harm to the unborn child R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S22 - Do not breathe dust. S23 - Do not breathe vapour. S36 - Wear suitable protective clothing. |
| UN IDs | UN1170 - class 3 - PG 2 - Ethanol, solution |
| WGK Germany | 3 |
| RTECS | SL1210000 |
68392-35-8 - Upstream Downstream Industry
68392-35-8 - Uses and synthesis methods
Target
Estrogen receptor
in vitro studies
4-OHT is an effective ER activator. Compared with tamoxifen, it has a higher affinity for estrogen receptors. 4-OHT has a strong dose and time-dependent effect, which can change the contractile function of isolated rat cardiomyocytes. 4-HT activates targeted modification efficiency of intein-Cas9 mutants.
Last Update：2024-04-10 22:29:15
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Product Name: Tamoxifen Citrate Impurity 25 Request for quotationCAS: 68392-35-8
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249
Wechat: 15787876101
Multiple SpecificationsSpot supply
Product Name: Afimoxifene Request for quotationCAS: 68392-35-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Afimoxifene Visit Supplier Webpage Request for quotationCAS: 68392-35-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: (E/Z)-4-Hydroxytamoxifen (Standard) Visit Supplier Webpage Request for quotationCAS: 68392-35-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Afimoxifene Visit Supplier Webpage Request for quotationCAS: 68392-35-8
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Spot supply
Product Name: (E/Z)-4-Hydroxy Tamoxifen Visit Supplier Webpage Request for quotationCAS: 68392-35-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
68392-35-8
13811-50-2
58111-94-7
649735-46-6
1011-13-8
媒介紫 1
2298-07-9
硅氯仿
Diethyl propanephosphonate
TANTALUM STANDARD
13811-50-2
58111-94-7
649735-46-6
1011-13-8
媒介紫 1
2298-07-9
硅氯仿
Diethyl propanephosphonate
TANTALUM STANDARD
Raw Materials for 68392-35-8
4-(1-(4-(2-bromoethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol(WXC07440)
4,4'-Dihydroxybenzophenone
Dimethylamine
Propiophenone
2-Dimethylaminoethyl chloride hydrochloride
N-PROPYLBENZENE
4,4'-Dihydroxybenzophenone
Dimethylamine
Propiophenone
2-Dimethylaminoethyl chloride hydrochloride
N-PROPYLBENZENE