7-Carboxyquinoline
Quinoline-7-carboxylic acid
CAS: 1078-30-4
Molecular Formula: C10H7NO2
7-Carboxyquinoline - Names and Identifiers
| Name | Quinoline-7-carboxylic acid |
| Synonyms | AKOS BBS-00005341 7-Carboxyquinoline 7-Quinolinecarboxylic acid 7-QUINOLINECARBOXYLIC ACID quinolin-7-carboxylic acid QUINOLINE-7-CARBOXYLIC ACID Quinoline-7-carboxylic acid 7-Carboxyquinoline, 7-Carboxy-1-azanaphthalene |
| CAS | 1078-30-4 |
| InChI | InChI=1/C10H7NO2/c12-10(13)8-4-3-7-2-1-5-11-9(7)6-8/h1-6H,(H,12,13) |
7-Carboxyquinoline - Physico-chemical Properties
| Molecular Formula | C10H7NO2 |
| Molar Mass | 173.17 |
| Density | 1.2427 (rough estimate) |
| Melting Point | 249.5°C |
| Boling Point | 303.81°C (rough estimate) |
| Flash Point | 164.7°C |
| Vapor Presure | 1.85E-05mmHg at 25°C |
| pKa | 2.68±0.30(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.5200 (estimate) |
7-Carboxyquinoline - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29334900 |
7-Carboxyquinoline - Introduction
7-Quinolinic acid, also known as 7-quinolinic acid, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 7-quinolinecarboxylic acid is white crystal or crystalline powder.
-Solubility: It is easily soluble in water and organic solvents such as ethanol and chloroform.
-Chemical properties: 7-quinolinecarboxylic acid is acidic and can react with alkali to generate the corresponding salt.
Use:
-Drug synthesis: 7-quinolinecarboxylic acid is an important intermediate, widely used in the pharmaceutical industry. It can be used to synthesize drugs with antiviral, antibacterial, anticancer and other activities.
-Pesticide synthesis: This compound can also be used to synthesize certain pesticides, such as pesticides and herbicides.
-Chemical research: 7-quinolinecarboxylic acid can be used in organic synthesis reactions and catalyst preparation and other fields.
Preparation Method:
- 7-quinolinecarboxylic acid can be synthesized by benzopyriquine reaction. The specific steps include the reaction of benzopyriquine with carbon monoxide to generate carbonyl compounds, and then carboxylation reaction to obtain 7-quinolinecarboxylic acid.
Safety Information:
-7-Quinolinic acid is relatively safe to the human body and the environment under normal conditions of use, but the following points still need to be noted:
-Contact: Avoid direct skin contact and wear gloves for handling.
-Inhalation: Avoid inhaling dust or aerosols. If inhalation occurs, please quickly move to a well-ventilated place.
-Eye contact: In case of eye splash, rinse immediately with plenty of water and seek medical advice.
-Storage: It should be kept in a dry, cool place, away from combustibles and oxidants.
-Waste Disposal: Disposal or recycling in accordance with local regulations.
Nature:
-Appearance: 7-quinolinecarboxylic acid is white crystal or crystalline powder.
-Solubility: It is easily soluble in water and organic solvents such as ethanol and chloroform.
-Chemical properties: 7-quinolinecarboxylic acid is acidic and can react with alkali to generate the corresponding salt.
Use:
-Drug synthesis: 7-quinolinecarboxylic acid is an important intermediate, widely used in the pharmaceutical industry. It can be used to synthesize drugs with antiviral, antibacterial, anticancer and other activities.
-Pesticide synthesis: This compound can also be used to synthesize certain pesticides, such as pesticides and herbicides.
-Chemical research: 7-quinolinecarboxylic acid can be used in organic synthesis reactions and catalyst preparation and other fields.
Preparation Method:
- 7-quinolinecarboxylic acid can be synthesized by benzopyriquine reaction. The specific steps include the reaction of benzopyriquine with carbon monoxide to generate carbonyl compounds, and then carboxylation reaction to obtain 7-quinolinecarboxylic acid.
Safety Information:
-7-Quinolinic acid is relatively safe to the human body and the environment under normal conditions of use, but the following points still need to be noted:
-Contact: Avoid direct skin contact and wear gloves for handling.
-Inhalation: Avoid inhaling dust or aerosols. If inhalation occurs, please quickly move to a well-ventilated place.
-Eye contact: In case of eye splash, rinse immediately with plenty of water and seek medical advice.
-Storage: It should be kept in a dry, cool place, away from combustibles and oxidants.
-Waste Disposal: Disposal or recycling in accordance with local regulations.
Last Update：2024-04-09 02:00:41
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