71170-88-2
1-(carbobenzyloxy)-2-piperidinecarboxylic acid
CAS: 71170-88-2;28697-07-6
Molecular Formula: C14H17NO4
71170-88-2 - Names and Identifiers
| Name | 1-(carbobenzyloxy)-2-piperidinecarboxylic acid |
| Synonyms | Z-PIPECOLIC ACID Z-PIPECOLINIC ACID 1-CBZ-2-PIPERIDINECARBOXYLIC ACID N-Cbz-Piperidine-2-carboxylic acid 1-CBZ-PIPERIDINE-2-CARBOXYLIC ACID N-CARBOBENZYLOXY-2-PIPERIDINECARBOXYLIC ACID N-Carbobenzyloxypiperidine-2-carboxylic acid 1-(CARBOBENZYLOXY)-2-PIPERIDINECARBOXYLIC ACID 1-(carbobenzyloxy)-2-piperidinecarboxylic acid PIPERIDINE-1,2-DICARBOXYLIC ACID 1-BENZYL ESTER 1-[(BENZYLOXY)CARBONYL]PIPERIDINE-2-CARBOXYLIC ACID (2R)-1-[(benzyloxy)carbonyl]piperidine-2-carboxylate (2S)-1-[(benzyloxy)carbonyl]piperidine-2-carboxylate |
| CAS | 71170-88-2 28697-07-6 |
| EINECS | 202-637-1 |
| InChI | InChI=1/C14H17NO4/c16-13(17)12-8-4-5-9-15(12)14(18)19-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10H2,(H,16,17)/p-1/t12-/m0/s1 |
71170-88-2 - Physico-chemical Properties
| Molecular Formula | C14H17NO4 |
| Molar Mass | 263.29 |
| Melting Point | 80-83°C(lit.) |
| Boling Point | 443.9°C at 760 mmHg |
| Flash Point | 222.3°C |
| Vapor Presure | 1.16E-08mmHg at 25°C |
| Storage Condition | Room Temprature |
71170-88-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| Hazard Note | Irritant |
71170-88-2 - Introduction
1-(carbobenzyloxy)-2-piperidinecarboxylic acid is an organic compound with a chemical formula of C19H19NO4 and a molecular weight of 321.36g/mol.
Nature:
1-(carbobenzyloxy)-2-piperidinecarboxylic acid is a white or yellowish solid with a characteristic aroma. It is stable at room temperature, soluble in organic solvents such as anhydrous aldehyde, anhydrous ketone, ether and dimethyl sulfoxide, and slightly soluble in ethanol and chloroform.
Use:
1-(carbobenzyloxy)-2-piperidinecarboxylic acid is a commonly used organic synthesis reagent, mainly used in the synthesis of drugs, pesticides and other organic compounds. It can be used as an intermediate in the synthesis of potential anticancer drugs, antiviral drugs and antibacterial agents. In addition, it can also be used in the synthesis of ligands and catalysts.
Preparation Method:
The preparation of 1-(carbobenzyloxy)-2-piperidinecarboxylic acid usually adopts chemical synthesis method. A common method is to react 2-piperidinecarboxylic acid with chloromethyl benzyl chloride to give 1-N-Cbz-2-piperidinecarbonyl chloride, which is then reacted with sodium bicarbonate to give 1-(carbobenzyloxy)-2-piperidinecarboxylic acid.
Safety Information:
1-(carbobenzyloxy)-2-piperidinecarboxylic acid generally does not have serious toxic effects on humans under normal operating conditions. However, as a chemical, it can have irritating and corrosive effects on the eyes, skin and mucous membranes. When using, avoid direct contact with skin and eyes, and ensure that the operation is carried out under well-ventilated conditions. Proper laboratory safety guidelines and personal protective measures should be followed when handling this compound. Seek immediate medical help if inhaled, ingested or in contact with skin.
Nature:
1-(carbobenzyloxy)-2-piperidinecarboxylic acid is a white or yellowish solid with a characteristic aroma. It is stable at room temperature, soluble in organic solvents such as anhydrous aldehyde, anhydrous ketone, ether and dimethyl sulfoxide, and slightly soluble in ethanol and chloroform.
Use:
1-(carbobenzyloxy)-2-piperidinecarboxylic acid is a commonly used organic synthesis reagent, mainly used in the synthesis of drugs, pesticides and other organic compounds. It can be used as an intermediate in the synthesis of potential anticancer drugs, antiviral drugs and antibacterial agents. In addition, it can also be used in the synthesis of ligands and catalysts.
Preparation Method:
The preparation of 1-(carbobenzyloxy)-2-piperidinecarboxylic acid usually adopts chemical synthesis method. A common method is to react 2-piperidinecarboxylic acid with chloromethyl benzyl chloride to give 1-N-Cbz-2-piperidinecarbonyl chloride, which is then reacted with sodium bicarbonate to give 1-(carbobenzyloxy)-2-piperidinecarboxylic acid.
Safety Information:
1-(carbobenzyloxy)-2-piperidinecarboxylic acid generally does not have serious toxic effects on humans under normal operating conditions. However, as a chemical, it can have irritating and corrosive effects on the eyes, skin and mucous membranes. When using, avoid direct contact with skin and eyes, and ensure that the operation is carried out under well-ventilated conditions. Proper laboratory safety guidelines and personal protective measures should be followed when handling this compound. Seek immediate medical help if inhaled, ingested or in contact with skin.
Last Update：2024-04-09 20:52:54
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QQ: 4006286883
CAS: 71170-88-2
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Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
Multiple SpecificationsSpot supply
Product Name: 1-Cbz-2-Piperidinecarboxylic Acid Visit Supplier Webpage Request for quotationCAS: 71170-88-2
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QQ: 2881950922
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Spot supply
Product Name: N-CBZ-piperidine-2-carboxylic acid Visit Supplier Webpage Request for quotationCAS: 71170-88-2
Tel: +86 0571-86722205
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Multiple Specifications
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View History
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