756525-91-4

756525-91-4 - Names and Identifiers

Name	BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
Synonyms	Boc-NH-PEG4-CH2CH2COOH BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID 15-(Boc-aMino)-4,7,10,13-tetraoxapentadecanoic acid N-(tert-Butyloxycarbonyl)-15-amino-4,7,10,13-tetraoxapentanedecanoic acid 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(1,1-dimethylethyl) ester 3-[2-[2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid 3-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CAS	756525-91-4
InChIKey	YCEYBRZRNOJORY-UHFFFAOYSA-N

756525-91-4 - Physico-chemical Properties

Molecular Formula	C16H31NO8
Molar Mass	365.42
Density	1.124±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	504.5±50.0 °C(Predicted)
pKa	4.28±0.10(Predicted)
Storage Condition	2-8°C
MDL	MFCD07781254
Physical and Chemical Properties	Bioactive Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker used to synthesize PROTAC. Boc-NH-PEG4-CH2CH2COOH is also a degradable ADC linker, which is used to synthesize degradable antibody-coupled drugs (ADC).

756525-91-4 - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29225090

756525-91-4 - Upstream Downstream Industry

Downstream Products

Maleimide-PEG4-NHS Ester

756525-91-4 - Nature

maximum wavelength (& lambda;max)

254nm(lit.)

Last Update：2024-04-10 22:29:15

756525-91-4 - Uses and synthesis methods

Target

PEGs

Alkyl/ether

in vitro studies

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Last Update：2024-04-10 22:29:15

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