7699-20-9
7-Methoxy-oxindole
CAS: 7699-20-9
Molecular Formula: C9H9NO2
7699-20-9 - Names and Identifiers
| Name | 7-Methoxy-oxindole |
| Synonyms | 7-METHOXYOXINDOLE 7-Methoxyoxindole 7-Methoxy-oxindole 7-Methoxy-2-oxindole 7-METHOXY-2-INDOLINONE 7-methoxyindolin-2-one 7-(Methylperoxy)-1H-indole 7-Methoxy-1,3-dihydro-2H-indol-2-one 7-Methoxy-2,3-dihydro-1H-indol-2-one 2H-Indol-2-one, 1,3-dihydro-7-methoxy- |
| CAS | 7699-20-9 |
| InChI | InChI=1S/C9H9NO2/c1-12-7-4-2-3-6-5-8(11)10-9(6)7/h2-4H,5H2,1H3,(H,10,11) |
7699-20-9 - Physico-chemical Properties
| Molecular Formula | C9H9NO2 |
| Molar Mass | 163.17 |
| Density | 1.208±0.06 g/cm3(Predicted) |
| Melting Point | 146 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 356.0±42.0 °C(Predicted) |
| Flash Point | 169.128 °C |
| pKa | 13.63±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
7699-20-9 - Introduction
7-Methoxy-oxindole(7-Methoxy-oxindole) is an organic compound with a chemical formula of C10H9NO2. Its molecular structure has an indole ring and an oxo ketone group.
Nature:
1. Appearance: 7-Methoxy-oxindole is a white crystalline solid.
2. Melting point: about 127-130°C.
3. Solubility: It can be dissolved in common organic solvents, such as ethanol, chloroform and dichloromethane.
Use:
7-Methoxy-oxindole has certain application value in the field of medicine, mainly for drug research and synthesis. It is a precursor of indole derivatives and can be used to synthesize other indole compounds through chemical reactions.
Preparation Method:
The preparation method of 7-Methoxy-oxindole can be realized by the following steps:
1. condensation reaction of indole and methine ketone to obtain pyran ring.
2. under alkaline conditions, methyl iodide is used for methylation reaction to generate 7-Methoxy-oxindole.
Safety Information:
1.7-Methoxy-oxindole should be stored in a dry, cool place, away from fire and oxidizing agents.
2. in the process of operation should take appropriate protective measures to avoid direct contact with the skin and breathing.
3. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
4. 7-The specific toxicity and danger of Methoxy-oxindole are not fully understood. Please follow the correct operating regulations and safety measures.
Nature:
1. Appearance: 7-Methoxy-oxindole is a white crystalline solid.
2. Melting point: about 127-130°C.
3. Solubility: It can be dissolved in common organic solvents, such as ethanol, chloroform and dichloromethane.
Use:
7-Methoxy-oxindole has certain application value in the field of medicine, mainly for drug research and synthesis. It is a precursor of indole derivatives and can be used to synthesize other indole compounds through chemical reactions.
Preparation Method:
The preparation method of 7-Methoxy-oxindole can be realized by the following steps:
1. condensation reaction of indole and methine ketone to obtain pyran ring.
2. under alkaline conditions, methyl iodide is used for methylation reaction to generate 7-Methoxy-oxindole.
Safety Information:
1.7-Methoxy-oxindole should be stored in a dry, cool place, away from fire and oxidizing agents.
2. in the process of operation should take appropriate protective measures to avoid direct contact with the skin and breathing.
3. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
4. 7-The specific toxicity and danger of Methoxy-oxindole are not fully understood. Please follow the correct operating regulations and safety measures.
Last Update：2024-04-09 15:17:59
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