79103-90-5
Polygalasaponin XXXI
CAS: 79103-90-5
Molecular Formula: C75H112O36
79103-90-5 - Names and Identifiers
79103-90-5 - Physico-chemical Properties
| Molecular Formula | C75H112O36 |
| Molar Mass | 1589.69 |
| Density | 1.53±0.1 g/cm3(Predicted) |
| Appearance | Powder |
| pKa | 4.14±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Easily absorbing moisture |
| In vitro study | Polygalasaponin XXXI (Onjisaponin F) also enhances anti-HA IgA and IgG Ab titers in the nasal wash, whereas Onjisaponins E and G enhances only anti-HA IgA Ab titer significantly. Polygalasaponin XXXI can induce protective immunity against intranasal infection by influenza virus. Polygalasaponin XXXI (Onjisaponin F) (1 or 10 µg/mL) also induces ChAT mRNA level in rat basal forebrain cells. |
| In vivo study | Intranasal vaccination with Polygalasaponin XXXI (Onjisaponin F) inhibits proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice. |
79103-90-5 - Reference Information
| biological activity | Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal injection of influenza HA vaccine, which can protect influenza virus infection |
| in vitro study | Polygalasaponin XXXI (Onjisaponin F) also enhances anti-HA IgA and IgG AB tiers in the nasal wash, whereas Onjisaponins E and G enhances only anti-HA IgA AB titer significantly. Polygalasaponin XXXI can induce protective immunity against intranasal infection by influenza virus. Polygalasaponin XXXI (Onjisaponin F) (1 or 10 µg/mL) also induces ChAT mRNA level in rat basic forebrain cells. |
| in vivo study | Intranasal vaccination with Polygalasaponin XXXI (Onjisaponin f) inhibits proliferation of mouse adapted influenza virus A/PR/8/34 in bronchoalveolar lavages of infected mice. |
Last Update：2024-04-09 21:49:45
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