846557-71-9
ML385
CAS: 846557-71-9
Molecular Formula: C31H29N3O2S
846557-71-9 - Names and Identifiers
846557-71-9 - Physico-chemical Properties
| Molecular Formula | C31H29N3O2S |
| Molar Mass | 507.6459 |
| Density | 1.374±0.06 g/cm3(Predicted) |
| Solubility | DMSO: ≥ 30 mg/mL |
| Appearance | Shape powder, color white to beige |
| pKa | 8.92±0.50(Predicted) |
| Storage Condition | 2-8°C |
| Physical and Chemical Properties | Bioactive ML385 is a new and specific NRF2 inhibitor with IC50 of 1.9 μM. It can inhibit the expression of the downstream target gene of NRF2. NRF2 modulates the activity of a variety of iron death and lipid peroxidation-related proteins. |
846557-71-9 - Reference
| Reference Show more | 1. [IF=6.543] Gong Wan et al."Orcinol Glucoside Improves Senile Osteoporosis through Attenuating Oxidative Stress and Autophagy of Osteoclast via Activating Nrf2/Keap1 and mTOR Signaling Pathway."Oxidative Medicine and Cellular Longevity. 2022;2022:5410377 |
846557-71-9 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.97 ml | 9.849 ml | 19.699 ml |
| 5 mM | 0.394 ml | 1.97 ml | 3.94 ml |
| 10 mM | 0.197 ml | 0.985 ml | 1.97 ml |
| 5 mM | 0.039 ml | 0.197 ml | 0.394 ml |
Last Update：2024-01-02 23:10:35
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