856405-77-1
9,9-Dimethyl-4,5-bis(di-tert-butylphosphino)xanthene
CAS: 856405-77-1
Molecular Formula: C31H48OP2
856405-77-1 - Names and Identifiers
| Name | 9,9-Dimethyl-4,5-bis(di-tert-butylphosphino)xanthene |
| Synonyms | t-Bu-Xantphos 9,9-Dimethyl-4,5-bis(di-t-butylphosphino)xanthene 9,9-Dimethyl-4,5-bis(di-tert-butylphosphino)xanthene 4,5-Bis[di(tert-butyl)phosphino]-9,9-dimethyl-9H-xanthene 4,5-Bis[Di(Tert-Butyl)Phosphino]-9,9-Dimethyl-9H-Xanthene (9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(di-tert-butylphosphine) Phosphine, 1,1'-(9,9-dimethyl-9H-xanthene-4,5-diyl)bis[1,1-bis(1,1-dimethylethyl)- |
| CAS | 856405-77-1 |
| InChI | InChI=1S/C31H48OP2/c1-27(2,3)33(28(4,5)6)23-19-15-17-21-25(23)32-26-22(31(21,13)14)18-16-20-24(26)34(29(7,8)9)30(10,11)12/h15-20H,1-14H3 |
856405-77-1 - Physico-chemical Properties
| Molecular Formula | C31H48OP2 |
| Molar Mass | 498.67 |
| Melting Point | 153-157℃ |
| Boling Point | 563.1±50.0 °C(Predicted) |
| Appearance | Powder |
| Color | white to light yellow |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
856405-77-1 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. |
| WGK Germany | 3 |
| TSCA | No |
856405-77-1 - Introduction
9,9-Dimethyl-4,5-bis(di-tert-butylphosphino)xanthene, abbreviated as DTXphos, is an organic compound with a chemical formula of C34H44P2O and a molecular weight of 528.63g/mol. It is a phosphine compound linked by two di-tert-butylphosphine groups at the position on the 4,5-benzo ring. The properties of this compound are as follows:
1. Appearance: The DTXphos is white to off-white solid.
2. Solubility: It can be dissolved in non-polar solvents, such as benzene, toluene and dichloromethane.
3. Thermal stability: The DTXphos is stable in air and can withstand short-term high temperature.
4. Organic solvent stability: The stability in organic solvents is good, but it may decompose under strong acid or strong alkali conditions.
DTXphos are mainly used in metal-catalyzed reactions, especially in asymmetric catalytic reactions catalyzed by transition metals. It forms complexes with transition metals and is used to catalyze carbonylation reactions and asymmetric hydrogenation reactions of carbonyl compounds. Because of its high catalytic performance and wide reaction applicability, DTXphos have been widely used in the fields of drug synthesis, material science and organic synthesis.
The preparation method of the DTXphos generally uses a common synthetic method in organic synthetic chemistry, such as an alkylation reaction or a nucleophilic substitution reaction. Many variations of the specific preparation method are possible, but a general procedure involves synthesizing a di-tert-butylphosphine compound and reacting it with 4,5-dibromobenzo, sodium metal and a solvent. After completion of the reaction, a pure DTXphos is obtained by mild workup and crystallization.
Regarding the safety information of the DTXphos, it is an organic compound, and the following matters should be paid attention to when using it:
1. DTXphos may be irritating to the eyes and skin. When operating, it is necessary to avoid contact with eyes and skin, and ensure that the operation is carried out in a well-ventilated place.
2. in the operation, should wear appropriate protective gloves and goggles, in order to avoid damage to the skin and eyes.
3. DTXphos should be stored in a dry, cool place, away from high temperature and fire.
4. when handling DTXphos, comply with laboratory and workplace safety procedures, avoid inhaling its vapor or dust.
It is important to note that the information provided above is for reference only. Please refer to relevant literature and ensure safe operation when operating and using.
1. Appearance: The DTXphos is white to off-white solid.
2. Solubility: It can be dissolved in non-polar solvents, such as benzene, toluene and dichloromethane.
3. Thermal stability: The DTXphos is stable in air and can withstand short-term high temperature.
4. Organic solvent stability: The stability in organic solvents is good, but it may decompose under strong acid or strong alkali conditions.
DTXphos are mainly used in metal-catalyzed reactions, especially in asymmetric catalytic reactions catalyzed by transition metals. It forms complexes with transition metals and is used to catalyze carbonylation reactions and asymmetric hydrogenation reactions of carbonyl compounds. Because of its high catalytic performance and wide reaction applicability, DTXphos have been widely used in the fields of drug synthesis, material science and organic synthesis.
The preparation method of the DTXphos generally uses a common synthetic method in organic synthetic chemistry, such as an alkylation reaction or a nucleophilic substitution reaction. Many variations of the specific preparation method are possible, but a general procedure involves synthesizing a di-tert-butylphosphine compound and reacting it with 4,5-dibromobenzo, sodium metal and a solvent. After completion of the reaction, a pure DTXphos is obtained by mild workup and crystallization.
Regarding the safety information of the DTXphos, it is an organic compound, and the following matters should be paid attention to when using it:
1. DTXphos may be irritating to the eyes and skin. When operating, it is necessary to avoid contact with eyes and skin, and ensure that the operation is carried out in a well-ventilated place.
2. in the operation, should wear appropriate protective gloves and goggles, in order to avoid damage to the skin and eyes.
3. DTXphos should be stored in a dry, cool place, away from high temperature and fire.
4. when handling DTXphos, comply with laboratory and workplace safety procedures, avoid inhaling its vapor or dust.
It is important to note that the information provided above is for reference only. Please refer to relevant literature and ensure safe operation when operating and using.
Last Update：2024-04-09 19:05:52
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Product Name: 9,9-Dimethyl-4,5-bis(di-t-butylphosphino)xanthene, min. 97% Visit Supplier Webpage Request for quotationCAS: 856405-77-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
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Product Name: 9,9-Dimethyl-4,5-bis(di-tert-butylphosphino)xanthene Request for quotation
CAS: 856405-77-1
Tel: 0086-13605431940
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Mobile: +86-13605431940
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CAS: 856405-77-1
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View History
856405-77-1
852-20-0
54367-66-7
61012-46-2
330645-87-9
3-[(3-MORPHOLINOPROPYL)AMINO]PROPANENITRILE
4-Methoxybenzhydrazide
doxcide50
PIERS-GRUBBS一代
氯氮䓬
852-20-0
54367-66-7
61012-46-2
330645-87-9
3-[(3-MORPHOLINOPROPYL)AMINO]PROPANENITRILE
4-Methoxybenzhydrazide
doxcide50
PIERS-GRUBBS一代
氯氮䓬