862372-66-5

862372-66-5 - Names and Identifiers

Name	3-Amino-1-Boc-pyrrolidine-3-carboxylic acid
Synonyms	3-Amino-1-(tert-butoxycarbonyl) 1-Boc-3-aMinopyrrolidine-3-carboxylic Acid 3-Amino-1-Boc-pyrrolidine-3-carboxylic acid 3-AMINO-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-T-BUTYL ESTER 3-Amino-Pyrrolidine-1,3-Dicarboxylic Acid 1-Tert-Butyl Ester 3-AMINO-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-AMINO-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-3-CARBOXYLIC ACID 3-Amino-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid 3-AMINO-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER-HCl 3-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid
CAS	862372-66-5
InChI	InChI=1/C10H18N2O4/c1-9(2,3)16-8(15)12-5-4-10(11,6-12)7(13)14/h4-6,11H2,1-3H3,(H,13,14)

862372-66-5 - Physico-chemical Properties

Molecular Formula	C10H18N2O4
Molar Mass	230.26
Density	1.243±0.06 g/cm3(Predicted)
Boling Point	365.2±42.0 °C(Predicted)
Flash Point	174.7°C
Vapor Presure	2.5E-06mmHg at 25°C
pKa	2.23±0.20(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.52

862372-66-5 - Risk and Safety

Hazard Class

IRRITANT

862372-66-5 - Introduction

The acid is an organic compound whose chemical formula is C11H19NO4.

Nature:
-acrylic is a white to off-white crystalline powder.
-It is stable at room temperature and soluble in organic solvents such as methanol, ethanol and dichloromethane.

Use:
-acid is an organic synthesis intermediate, commonly used in the synthesis of various amino acids and peptides.
-It can be converted into pyrrolidine-3-carboxylic acid (pyrrolidine acid) by the reaction of the deprotecting group (Boc group).

Preparation Method:
There are many methods for preparing acid. A common method is to react 3-amino-1-pyrrolidine-3-carboxylic acid with Boc acid chloride. The specific preparation process is as follows:
-Dissolve 3-amino-1-pyrrolidine-3-carboxylic acid and base (such as triethylamine) in an organic solvent, and add Boc acid chloride;
-Stir the reaction at an appropriate temperature for several hours. After the reaction is complete, filter the mixture;
-Further purify the mixture to obtain acid.

Safety Information:
-must acid is relatively stable under general conditions of use.
-During operation, care should be taken to avoid skin contact and inhalation of its dust.
-Operation should be carried out in a well-ventilated place, and respiratory protection equipment and chemical protective clothing should be used if necessary.
-If ingested, inhaled or in contact with skin, seek medical attention immediately.

Last Update：2024-04-10 22:29:15