87579-78-0

87579-78-0 - Names and Identifiers

Name	BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE]
Synonyms	Tazobactam Impurity 44 Tazobactam Acid Impurity 24 BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE] (2S,5R)-Benzhydryl 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2- (2S,5R)-Benzhydryl 3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid diphenylmethyl ester 4-oxide (2S,5R)-3,3-dimethyl-7-oxo-4- oxide-4-Thia-1-azabicyclo[3.2. 0]heptane-2-carboxylic Acid Diphenylmethyl Ester 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, diphenylmethyl ester, 4-oxide, (2S,5R)-
CAS	87579-78-0

87579-78-0 - Physico-chemical Properties

Molecular Formula	C21H21NO4S
Molar Mass	383.46
Density	1.37
Boling Point	598.7±50.0 °C(Predicted)
Solubility	Dichloromethane
Appearance	Solid
Color	Yellow
pKa	-3.44±0.60(Predicted)
Storage Condition	2-8°C

87579-78-0 - Introduction

BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE [TAZOBACTAM INTERMEDIATE](BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE [TAZOBACTAM INTERMEDIATE]) is an organic compound with the chemical formula C19H15NO4S. Here are some of the properties of the compound:

Nature:
-Appearance: White crystalline solid
-Molecular weight: 357.39g/mol
-Melting point: 151-156°C
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol, acetone and dimethyl sulfoxide

Use:
BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE] is a drug intermediate, mainly used to synthesize the antibiotic ceftaperidone (Tazobactam). Ceftamperone is a β-lactam antibiotic that is often used in combination with other antibiotics to enhance its efficacy against multidrug-resistant bacteria.

Preparation Method:
The preparation method of BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE] is relatively complicated, and in most cases, it needs to be synthesized by multi-step reaction. A common method is to start from penicillane (Penicillin) and go through several steps to finally obtain the target compound.

Safety Information:
Under the correct operation and storage conditions, BENZHYDRYL 6,6-DIHYDROPENICILLIC ACID 1-OXIDE[TAZOBACTAM INTERMEDIATE] is generally stable. However, as an organic compound, it may produce certain toxicity and irritation to human body. Therefore, appropriate laboratory practices should be followed during use and necessary personal protective measures should be taken, such as wearing gloves and goggles. If necessary, operate in a well-ventilated environment. When storing, it should be kept in a dry, cool place, away from fire and oxidant.

Last Update：2024-04-09 20:48:19