876317-19-0

876317-19-0 - Names and Identifiers

Name	1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid
Synonyms	1-(tert-Butoxycarbonyl)-4-oxoproline BOC- 4-OXOPYRROLIDINE-2-CARBOXYLIC ACID 4-OXOPYRROLIDINE-2-CARBOXYLIC ACID, N-BOC PROTECTED 1-tert-(Butoxycarbonyl)pyrrolidin-4-one-2-carboxylic acid 4-OXO-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 1-(TERT-BUTOXYCARBONYL)-4-OXOPYRROLIDINE-2-CARBOXYLIC ACID 1-(tert-butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid (2S)-1-TERT-BUTYL HYDROGEN 4-OXOPYRROLIDINE-1,2-DICARBOXYLATE 1,2-pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-dimethylethyl) ester
CAS	876317-19-0
InChI	InChI=1/C10H15NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h7H,4-5H2,1-3H3,(H,13,14)

876317-19-0 - Physico-chemical Properties

Molecular Formula	C10H15NO5
Molar Mass	229.23
Density	1.304±0.06 g/cm3(Predicted)
Melting Point	155 °C
Boling Point	390.8±42.0 °C(Predicted)
Flash Point	190.123°C
Vapor Presure	0mmHg at 25°C
pKa	3.85±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.516

876317-19-0 - Introduction

1-(tert-butoxycarbonyl)-acid is an organic compound with the chemical formula C10H15NO4.

Properties: 1-(tert-butoxycarbonyl)-acid is a white crystalline solid, stable at room temperature. It is soluble in organic solvents such as dimethyl sulfoxide and practically insoluble in water.

use: 1-(tert-butoxycarbonyl)-acid is often used as a protecting group in organic synthesis, and can be added to the compound through acylation reaction to protect the carboxylic acid group in the reaction. In the field of synthetic peptides and pharmaceuticals, it is widely used to protect amino acids and carboxylic acids of polypeptides to prevent unwanted reactions from occurring.

Preparation method: 1-(tert-butoxycarbonyl)-The preparation of acid is generally obtained by reacting pyrrolidine-2-carboxylic acid with a tert-butoxycarbonylation agent. The reaction is usually carried out under an inert atmosphere to avoid the influence of oxygen in the air.

Safety information: 1-(tert-butoxycarbonyl)-The acid is generally relatively safe under normal use conditions. However, as an organic compound, it may have an irritating effect on the skin, eyes and respiratory tract. Therefore, personal protective measures should be taken to avoid direct contact during handling and use. At the same time, follow the safe operation procedures of the laboratory to prevent accidental ingestion and inhalation, and store properly, away from fire and oxidant. In case of accidental exposure or discomfort, medical help should be sought immediately.

Last Update：2024-04-09 21:11:58