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876345-13-0

Boc-NH-PEG(3)-COOH

CAS: 876345-13-0

Molecular Formula: C15H29NO8

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876345-13-0 - Names and Identifiers

Name Boc-NH-PEG(3)-COOH
Synonyms Boc-NH-PEG(3)-COOH
Boc-NH-(PEG)4-CH2COOH
t-Boc-N-amido-PEG4-CH2CO2H
Boc-NH-PEG(3)-COOH(16atoMs)
t-boc-N-amido-PEG4-acetic acid
14-(Boc-amino)-3,6,9,12-tetraoxatetradecan-1-oic Acid
2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid
5,8,11,14-Tetraoxa-2-azahexadecanedioic acid, 1-(1,1-dimethylethyl) ester
CAS 876345-13-0

876345-13-0 - Physico-chemical Properties

Molecular FormulaC15H29NO8
Molar Mass351.39
Density1.138±0.06 g/cm3(Predicted)
Boling Point493.6±40.0 °C(Predicted)
pKa3.39±0.10(Predicted)
Storage Condition-20°C
In vitro study ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

876345-13-0 - Reference Information

biological activity Boc-NH-PEG4-CH2COOH is a degradable ADC linker, which is used to synthesize degradable antibody conjugated drugs (ADC) ADC linker. Boc-NH-PEG4-CH2COOH is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.
target Cleavable Alkyl/ether PEGs
in vitro study ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Last Update:2024-04-09 21:21:28
876345-13-0
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Shanghai Yuanye Bio-Technology Co., Ltd.
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