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887650-05-7

Bafetinib

CAS: 887650-05-7;859217-05-3;859212-16-1

Molecular Formula: C30H31F3N8O

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887650-05-7 - Names and Identifiers

Name Bafetinib
Synonyms Lyn-IN-1
bafetinib
Bafetinib
Bafetinib analog
(S)-N-(3-(5,5'-Bipyrimidin-2-ylamino)-4-methylphenyl)-4-((3-(dimethylamino)-pyrrolidin-1-yl)me
(S)-N-(3-([5,5'-bipyriMidin]-2-ylaMino)-4-Methylphenyl)-4-((3-(diMethylaMino)pyrrolidin-1-yl)Methyl)-3-(trifluoroMethyl)benzaMide
N-[3-([5,5'-Bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzamide
N-{3-[([5,5'-bipyrimidin]-2-yl)amino]-4-methylphenyl}-4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide
Benzamide, N-[3-([5,5'-bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)-
CAS 887650-05-7
859217-05-3
859212-16-1
EINECS 1312995-182-4

887650-05-7 - Physico-chemical Properties

Molecular FormulaC30H31F3N8O
Molar Mass576.62
Density1.36
Melting Point>166°C (dec.)
Solubility DMSO, Methanol
AppearanceSolid
ColorYellow
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C
Physical and Chemical PropertiesAppearance: white or white-like crystalline powder
Dissolution: dissolved in DMSO (up to 100 mM)
Preservation: 3 years -20 ℃ powder
Figure 1 shows bafitinib
UseBafetinib (INNO-406) is an effective, selective, Bcr-Abl/Lyn dual inhibitor with IC50 of 5.8 nM/19 nM. It has no inhibitory effect on phosphorylation of T315I mutant, and has a slightly weaker effect on PDGFR and c-Kit.

887650-05-7 - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.734 ml8.671 ml17.342 ml
5 mM0.347 ml1.734 ml3.468 ml
10 mM0.173 ml0.867 ml1.734 ml
5 mM0.035 ml0.173 ml0.347 ml
Last Update:2024-01-02 23:10:35
887650-05-7
Supplier List
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsMultiple SpecificationsSpot supply
Product Name: Bafetinib (INNO-406) Visit Supplier Webpage Request for quotation
CAS: 859212-16-1
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Shanghai Amole Biotechnology Co., Ltd.
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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CAS: 887650-05-7
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MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: INNO-406; NS-187 Visit Supplier Webpage Request for quotation
CAS: 859212-16-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Bafetinib (INNO-406) Visit Supplier Webpage Request for quotation
CAS: 859212-16-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsMultiple SpecificationsSpot supply
Product Name: Bafetinib (INNO-406) Visit Supplier Webpage Request for quotation
CAS: 859212-16-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Lyn-IN-1 Request for quotation
CAS: 887650-05-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Multiple SpecificationsSpot supply
Product Name: Lyn-IN-1 Visit Supplier Webpage Request for quotation
CAS: 887650-05-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: INNO-406; NS-187 Visit Supplier Webpage Request for quotation
CAS: 859212-16-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Bafetinib (INNO-406) Visit Supplier Webpage Request for quotation
CAS: 859212-16-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
887650-05-7
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