2 '-deoxyguanosine-5'-monophosphate (2 '-deoxyguanosine 5'-monophosphate) is a nucleotide consisting of deoxyguanosine and monophosphate. It has the following properties:
1. Appearance: colorless or white crystalline powder.
2. Solubility: Soluble in water and buffer.
3. Molecular formula and relative molecular mass: C10H15N5O9P, molecular weight of 365.23g/mol.
2 '-deoxyguanosine-5'-monophosphate has a wide range of uses in biological and pharmaceutical research, including the following:
1. The substrate of DNA synthesis reaction: as a single nucleotide unit in DNA synthesis, it is used to construct DNA molecules.
2. Antiviral drug research: for the development of antiviral drugs against viral infections.
3. Substrates for biochemical reactions: used to study biochemical processes such as gene expression and protein synthesis.
4. Molecular biological markers: can be used as molecular markers for DNA or RNA detection and research.
2 '-deoxyguanosine-5'-monophosphate can be prepared by a synthetic method. A common preparation method is to react deoxyguanosine with a phosphating reagent, 2 '-deoxyguanosine-5'-monophosphate is generated.
Regarding safety information, there are relatively few safety and toxicity studies on 2 '-deoxyguanosine-5'-monophosphate, but it is generally considered to be a relatively safe compound. However, any chemical should be handled with care. When using or handling 2 '-deoxyguanosine-5'-monophosphate, it is recommended to follow laboratory safety practices, wear appropriate personal protective equipment, and strictly control its use and storage. Such as accidental contact or ingestion, should take appropriate emergency measures in a timely manner, and seek medical help.