9072-19-9
fucoidan from fucus vesiculosus Fucoidan
CAS: 9072-19-9
Molecular Formula: (C12H18CaO14S2)n=(490.48)
9072-19-9 - Names and Identifiers
| Name | fucoidan from fucus vesiculosus Fucoidan |
| Synonyms | fucoidan from fucus vesiculosus Fucoidan Fraction 7, Fucus vesiculosus FUCOIDAN FROM FUCUS VESICULOSUS |
| CAS | 9072-19-9 |
9072-19-9 - Physico-chemical Properties
| Molecular Formula | (C12H18CaO14S2)n=(490.48) |
| Water Solubility | H2O: soluble10mg/mL, clear to hazy, faintly yellow to brownish-yellow |
| Storage Condition | Room Temprature |
| MDL | MFCD00131109 |
| Use | Fucoidan has a strong role in promoting cancer cell apoptosis and immune balance and promote tissue cell regeneration, cancer has become the second largest "killer disease" in the world, second only to cardiovascular disease, which seriously endangers human health. The new discovery of the anticancer effect of fucoidan undoubtedly adds a new weapon to the fight against tumor. |
9072-19-9 - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
9072-19-9 - Reference
| Reference Show more | 1. Liu Xin, Cui Maosheng, Zhang Dan, etc. Comparative Experiment on the effect of preservative agent for pig fresh concentrate at 17 ℃ [J]. China animal seed industry, 2019, 15(02):88-89. 2. [IF = 5.268] Juanjuan Yang et al."Effect of Laminaria japonica polysaccharides on lipids monolayers at the air-water surface." Colloid Surface B. 2018 Jan;161:614 3. [IF=5.118] Zhihui Ma et al."The Emerging Evidence for a Protective Role of Fucoidan from Laminaria japonica in Chronic Kidney Disease-Triggered Cognitive Dysfunction."Mar Drugs. 2022 Apr;20(4):258 |
9072-19-9 - Antioxidant properties of fucoidan sulfate in vitro
From Titanium Academic
Author:
Xue Changhu ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(6 d4ab291ce219a68) author:(Chen lei)" target = "_blank"> Chen lei ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(c23a073c5e34f3d4) author:(Li zhaojie)" target = "_blank"> Li zhao href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(83749915 ce439674) author:(Xin mei)" target = "_blank"> Xin mei ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(5802 f478143aec2d) author:(Lin hong)" target = "_blank"> Lin hong ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(91 a2c8afd43f36b) author:(Yu guangli)" target = "_blank"> Yu guangli /P>
Summary:
the effect of fucoidan sulfate on scavenging superoxide anion radical (O -2) and hydroxyl radical (OH) was studied by chemiluminescence analysis, and the inhibitory ability of lecithin (PC) peroxidation was studied by high performance liquid chromatography. The results show that:(1) the three fucoidan sulfate components have the ability to scavenge reactive oxygen species free radicals, but the ability to scavenge superoxide anion free radicals is higher than the ability to scavenge dangerous poor radicals. Among them, component I with high uronic acid content and low sulfate content has the strongest ability to scavenge free radicals, and its IC50 to O -2 is 0.044 mg/mL, the IC50 for OH is 0.062 mg/mL.(2) fucoidan thioester has the ability to inhibit C peroxidation. After fucoidan thioester components are damaged by activity, their antioxidant ability is reduced. Studies have shown that fucoidan has strong antioxidant function in vitro.
keywords:
fucoidan chemiluminescence analysis reactive oxygen radicals lipid peroxidation
DOI:
10.3969/j.issn.1672-5174.2000.04.004
cited:
Year:
2000
Last Update：2024-01-02 23:10:35
9072-19-9 - Study on the lipid-lowering and antioxidant effects of fucoidan
From HowNet
Author:
Li Zhaojie ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(f31f9b145f5a013e) author:(Xue Changhu)" target = "_blank"> Xue Changhu ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(594 fe34114e43ea4) author:(Lin Hong)" target = "_blank"> Lin Hong href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(c384a9565da7f732) author:(Wang Jingfeng)" target = "_blank"> Wang Jingfeng ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(cd2926373e020ca3) author:(Cai Yue Piao)" target = "_blank"> Cai Yue Piao ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(83749915 ce439674) author:(Xin Mei)" target = "_blank"> Xin Mei
Summary:
to observe the effect of low molecular weight fucoidan polythioate on blood lipid level, lipid peroxide content and SOD activity in serum and tissues of experimental hyperlipidemia rats, and to explore the relationship between its lipid lowering, antioxidant effect and anti-atherosclerosis.
keywords:
LMSF hyperlipidemia lipid peroxide SOD
DOI:
10.1088/0256-307X/16/12/025
cited:
Year:
1999
Last Update：2023-08-16 22:23:51
9072-19-9 - Study on Extraction of Fucoidan from kelp by Enzymatic Hydrolysis with Complex Enzyme
from Baidu library
Author:
he yunhai , Wang qiukuan , Liu Hongdan
Summary:
the technological parameters for extracting fucoidan sulfate from kelp Laminaria japonica by pentosan complex enzyme and complex cellulase were studied by orthogonal test. The results showed that the optimum enzymatic hydrolysis parameters of kelp by pentosan complex enzyme were enzyme dosage 0.06%, temperature 40 ℃,pH 3.5, enzymolysis time 30min, extraction rate of fucoidan sulfate 1.845%, and mass fraction of total sulfate in crude extract 0.238%. The optimum enzymatic hydrolysis parameters for kelp by complex cellulase are enzyme dosage 0.208%, temperature 50 ℃,pH 4.5, enzymolysis time 50min, the extraction rate of fucoidan sulfate was 1.279%, and the total sulfate content in the crude extract was 0.231%. The extraction rate of fucoidan crude extract extracted by enzymatic hydrolysis of two kinds of complex enzymes is higher than that of boiling method (0.968%).
keywords:
fucoidan enzymolysis extraction process
DOI:
10.3969/j.issn.1000-9957.2006.01.011
cited:
Year:
2006
Last Update：2023-08-16 22:23:51
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