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93987-29-2

2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole

CAS: 93987-29-2

Molecular Formula: C15H13N3O4S

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93987-29-2 - Names and Identifiers

Name 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole
Synonyms BI 6015
BI-6015
2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole
2-Methyl-1-[(2-methyl-5-nitrophenyl)sulfonyl]-1H-benzimidazole
2-Methyl-1-(2-methyl-5-nitrophenylsulfonyl)-1H-benzo[d]imidazole
CAS 93987-29-2

93987-29-2 - Physico-chemical Properties

Molecular FormulaC15H13N3O4S
Molar Mass331.35
Solubility Soluble in DMSO
AppearanceBeige powder
ColorTan
Storage Condition+2C to +8C
StabilityStable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
UseBI6015 is a small molecule antagonist of Hepatocyte nuclear factor 4α (HNF4α) that has been shown to repress the expression of known HNF4α target genes.

93987-29-2 - Reference

Reference
Show more
1: Mayati A, Le Vee M, Moreau A, Jouan E, Bucher S, Stieger B, Denizot C, Parmentier Y, Fardel O. Protein kinase C-dependent regulation of human hepatic drug transporter expression. Biochem Pharmacol. 2015 Dec 15;98(4):703-17. doi: 10.1016/j.bcp.2015.10.007. PubMed PMID: 26462574.
2: Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F. HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chem Biol. 2012 Jul 27;19(7):806-18. doi: 10.1016/j.chembiol.2012.05.014. PubMed PMID: 22840769; PubMed Central PMCID: PMC3447631.

93987-29-2 - Preparation solution concentration reference

 1mg5mg10mg
1 mM3.018 ml15.09 ml30.18 ml
5 mM0.604 ml3.018 ml6.036 ml
10 mM0.302 ml1.509 ml3.018 ml
5 mM0.06 ml0.302 ml0.604 ml
Last Update:2024-01-02 23:10:35

93987-29-2 - Introduction

2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole is a chemical substance that belongs to the group of organic compounds. The following is a description of the nature, use, preparation and safety information of 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzidazole:

Nature:
-Appearance: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole is a solid, which may have different colors, such as white or yellow.
-Solubility: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole has good solubility in some organic solvents, but it is almost insoluble in water.
-Stability: 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole is relatively stable at room temperature, but may decompose or oxidize in the presence of high temperature, light or oxygen.

Use:
-Research: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole is commonly used in scientific research, especially in some biochemical and pharmaceutical research.
-Coordination compound: 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole can also be used to synthesize metal complexes, these complexes may have important applications in catalytic reactions.

Preparation Method:
-Main synthesis method: 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole has many synthesis methods, one of which is through organic synthesis reaction, such as amidation reaction, acylation reaction, etc.
-Laboratory preparation: Generally, 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole can be synthesized from the corresponding starting material through a series of synthetic steps.

Safety Information:
-Toxicity: There is limited information on the toxicity of 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole, but based on the experience of general chemicals, we need to handle and use it carefully.
-Avoid Contact: When handling 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole, appropriate laboratory safety measures should be taken, such as wearing gloves and protective glasses with eyepieces, to reduce skin and eye contact.
-Storage: 2-methyl-1-(2-methyll-5-nitrophenyl) sulfonylbenzimidazole should be stored in a dry, cool place, away from fire and oxidizing agents.

Please note that for more specific information on the nature, use, formulation and safety of 2-methyl-1-(2-methyll-5-nitrophenyl) sulphonylbenzimidazole, further review of the literature or consultation with chemical experts is required.
Last Update:2024-04-09 15:16:34
93987-29-2
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Shanghai Macklin Biochemical Co., Ltd
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: BI-6015 Visit Supplier Webpage Request for quotation
CAS: 93987-29-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: 2-Methyl-1-((2-methyl-5-nitrophenyl)sulfonyl)-1H-benzo[d]imidazole Request for quotation
CAS: 93987-29-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: BI-6015 Visit Supplier Webpage Request for quotation
CAS: 93987-29-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: BI-6015 Visit Supplier Webpage Request for quotation
CAS: 93987-29-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: 2-methyl-1-(2-methyl-5-nitrophenyl)sulfonylbenzimidazole Visit Supplier Webpage Request for quotation
CAS: 93987-29-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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