BOC-D-GLU(OTBU)-OH
BOC-D-GLU(OTBU)-OH
CAS: 104719-63-3
Molecular Formula: C14H25NO6
BOC-D-GLU(OTBU)-OH - Names and Identifiers
BOC-D-GLU(OTBU)-OH - Physico-chemical Properties
| Molecular Formula | C14H25NO6 |
| Molar Mass | 303.35 |
| Density | 1.121 |
| Boling Point | 449.8±40.0 °C(Predicted) |
| Appearance | Solid |
| BRN | 3594191 |
| pKa | 3.82±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| MDL | MFCD00076927 |
BOC-D-GLU(OTBU)-OH - Risk and Safety
| WGK Germany | 3 |
| HS Code | 2924 19 00 |
BOC-D-GLU(OTBU)-OH - Introduction
BOC-D-glutamic acid-5-tert-butyl ester (BOC-D-GLU(OTBU)-OH) is an organic compound with the following properties:
1. Appearance: white to yellowish solid.
2. Molecular formula: C16H25NO7.
3. Molecular weight: 343.4g/mol.
4. Melting Point: 64-66 ℃.
5. Solubility: Soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF).
The main use of this compound is as a protective group in the field of organic synthesis. It can react with amino acid residues to form temporary protecting groups to prevent non-specific chemical reactions. In the synthesis of polypeptides or proteins, BOC-D-glutamic acid 5-tert-butyl ester can be used to protect the amine groups of glutamic acid residues.
The production method of BOC-D-glutamic acid -5-tert-butyl ester is generally obtained by a BOC-protected amino acid synthesis method. The specific steps include reacting D-glutamic acid with tert-butyl chloroformate (BOC-Cl) to produce BOC-D-glutamic acid -5-tert-butyl ester. The reaction process requires the use of alkaline solution and inert atmosphere for protection.
Regarding safety information, BOC-D-glutamic acid -5-tert-butyl ester is generally relatively safe under normal operating conditions. However, it can be irritating to the eyes, skin and respiratory tract. Necessary safety measures should be taken during operation, such as wearing protective glasses, gloves and respiratory protection equipment. Avoid inhaling dust of the compound or contact with skin. If necessary, operate in a well-ventilated laboratory environment and handle and store in accordance with safe operating instructions.
1. Appearance: white to yellowish solid.
2. Molecular formula: C16H25NO7.
3. Molecular weight: 343.4g/mol.
4. Melting Point: 64-66 ℃.
5. Solubility: Soluble in polar organic solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF).
The main use of this compound is as a protective group in the field of organic synthesis. It can react with amino acid residues to form temporary protecting groups to prevent non-specific chemical reactions. In the synthesis of polypeptides or proteins, BOC-D-glutamic acid 5-tert-butyl ester can be used to protect the amine groups of glutamic acid residues.
The production method of BOC-D-glutamic acid -5-tert-butyl ester is generally obtained by a BOC-protected amino acid synthesis method. The specific steps include reacting D-glutamic acid with tert-butyl chloroformate (BOC-Cl) to produce BOC-D-glutamic acid -5-tert-butyl ester. The reaction process requires the use of alkaline solution and inert atmosphere for protection.
Regarding safety information, BOC-D-glutamic acid -5-tert-butyl ester is generally relatively safe under normal operating conditions. However, it can be irritating to the eyes, skin and respiratory tract. Necessary safety measures should be taken during operation, such as wearing protective glasses, gloves and respiratory protection equipment. Avoid inhaling dust of the compound or contact with skin. If necessary, operate in a well-ventilated laboratory environment and handle and store in accordance with safe operating instructions.
Last Update：2024-04-10 22:29:15
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