Bioymifi
Bioymifi
CAS: 1420071-30-2
Molecular Formula: C22H12BrN3O4S
Bioymifi - Names and Identifiers
Bioymifi - Physico-chemical Properties
| Molecular Formula | C22H12BrN3O4S |
| Molar Mass | 494.32 |
| Solubility | DMSO: soluble2mg/mL, clear (warmed) |
| Appearance | powder |
| Color | , orange to dark orange red |
| Storage Condition | 2-8°C |
| In vitro study | Bioymifi (3-10 µM) induces caspase-8-dependent apoptosis. At a 10-μM concentration, Bioymifi induces processing of caspase-3 into smaller fragments. Bioymifi induces apoptosis via death receptor DR5. Bioymifi promotes DR5 aggregation and activation. Bioymifi shares the same DR5-dependent extrinsic apoptotic pathway with TRAIL. Binding of bioymifi to DR5 recruits FADD, which in turn engages with the apical caspase-8 to form death-inducing signaling complex (DISC) Bioymifi (3-10 µM) induces caspase-8-dependent apoptosis. At a 10-μM concentration, Bioymifi induces processing of caspase-3 into smaller fragments. |
Bioymifi - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
Bioymifi - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 0 ml | 0 ml | 0 ml |
| 5 mM | 0 ml | 0 ml | 0 ml |
| 10 mM | 0 ml | 0 ml | 0 ml |
| 5 mM | 0 ml | 0 ml | 0 ml |
Last Update：2024-01-02 23:10:35
Bioymifi - Reference Information
| biological activity | biomymifi is a potent activator of the TRAIL receptor DR5, and the extracellular domain (ECD) of DR5 combined, with a Kd of 1.2 μm, Bioymifi can induce aggregation of DR5 as a single inducer, leading to apoptosis. |
| in vitro study | Bioymifi (3-10 µm) induces caspase-8-dependent apotosis. At a 10-μm concentration, bioymifes processing of caspase-3 into smaller fragments. Bioypifi agents interactions via death receptor DR5. Bioymifi shares the same DR5-dependent extrinsic apoptic pathway with TRAIL. Binding of bioymifi to DR5 cruises FADD, which in turn engages with the apical caspase-8 to form death-inducing signaling complex (DISC) Bioymifi (3-10 µM) induces caspase-8-dependent apoptosis. At a 10-μM concentration, Bioymifi induces processing of caspase-3 into smaller fragments. |
Last Update：2024-04-10 22:41:03
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Email: Int06@meryer.com
Mobile: +86-18821248368
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Product Name: Bioymifi Request for quotationCAS: 1420071-30-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
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Product Name: Bioymifi Visit Supplier Webpage Request for quotationCAS: 1420071-30-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: DR5 Activator Visit Supplier Webpage Request for quotationCAS: 1420071-30-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Bioymifi Visit Supplier Webpage Request for quotationCAS: 1420071-30-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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