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Bisoprolol

1-[isopropylamino]-3-[isopropoxyethoxymethylphenoxy]-2-propanol

CAS: 66722-44-9

Molecular Formula: C18H31NO4

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Bisoprolol - Names and Identifiers

Name 1-[isopropylamino]-3-[isopropoxyethoxymethylphenoxy]-2-propanol
Synonyms BISOPROLOL
Bisoprolol
Bisoprolol base
Bisoprolol-d5 HeMifuMarate
1-[isopropylamino]-3-[isopropoxyethoxymethylphenoxy]-2-propanol
1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)-2-propanol
1-(4-((2-isopropoxyethoxy)Methyl)phenoxy)-3-(isopropylaMino)propan-2-ol
(R)-1-(Isopropylamino)-3-[4-(2-isopropoxyethoxymethyl)phenoxy]-2-propanol
1-[(1-Methylethyl)amino]-3-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-2-propanol
(R)-1-[(1-Methylethyl)amino]-3-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-2-propanol
1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-( isopropylamino)-2-propanol fumaric acid salt
CAS 66722-44-9
EINECS 613-980-5
InChI InChI=1/C18H31NO4/c1-14(2)19-11-17(20)13-23-18-7-5-16(6-8-18)12-21-9-10-22-15(3)4/h5-8,14-15,17,19-20H,9-13H2,1-4H3

Bisoprolol - Physico-chemical Properties

Molecular FormulaC18H31NO4
Molar Mass325.44
Density1.033±0.06 g/cm3(Predicted)
Melting Point100 °C
Boling Point445.0±45.0 °C(Predicted)
Water Solubility5.5ug/L(100 ºC)
Solubility Chloroform (Sparingly), Methanol (Slightly)
Appearanceneat
ColorYellow
pKapKa 9.57(H2O(extrap) t=25±1 Iunde?ned Aratmosphere) (Uncertain)
Storage Condition-20°C Freezer, Under Inert Atmosphere
UseFor the treatment of cardiovascular and cerebrovascular diseases

Bisoprolol - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk Codes22 - Harmful if swallowed
WGK Germany1
RTECSUB8380000
Hazard ClassIRRITANT

Bisoprolol - Nature

Open Data Verified Data

Bisoprolol hemifumarate Crystal, melting point 100 °c. Soluble in ethanol.

Last Update:2024-01-02 23:10:35

Bisoprolol - Preparation Method

Open Data Verified Data

4-[(2-isopropoxyethoxy) methyl] phenol is reacted with epichlorohydrin, and the resulting epoxide is reacted with isopropylamine to obtain Bisoprolol.

Last Update:2025-06-10 22:55:16

Bisoprolol - Application

Open Data Verified Data

developed by E.Merock, Germany, launched in 1986. It is a β1-blocker with high affinity and selectivity for cardiac-receptors, and its β1-selectivity is higher than that of cardiac-selective β1-blockers such as Atenolol and metoprolol. No cell membrane stabilizing effect in the therapeutic dose range. It is used for hypertension and coronary heart disease, and is relatively safe for hypertensive patients with asthma.

Last Update:2025-08-19 16:24:40
Bisoprolol
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Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Bisoprolol Request for quotation
CAS: 66722-44-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Bisoprolol Visit Supplier Webpage Request for quotation
CAS: 66722-44-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
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Bisoprolol
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