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CTP

CTP

CAS: 65-47-4

Molecular Formula: C9H16N3O14P3

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CTP - Names and Identifiers

Name CTP
Synonyms CTP
5'-ctp
cytidinetriphosphate
cytidine3'-triphosphate
CYTIDINE 5'-TRIPHOSPHATE
cytidine5'-triphosphoricacid
cytidine5'-(tetrahydrogentriphosphate)
cytidine,5'-(tetrahydrogentriphosphate)
[[[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
CAS 65-47-4
EINECS 200-611-4

CTP - Physico-chemical Properties

Molecular FormulaC9H16N3O14P3
Molar Mass483.16
Storage Condition2-8°C
Physical and Chemical PropertiesThe chemical product is white powder, tasteless, odorless, and hygroscopic. It is easily soluble in water and slightly soluble in organic solvents such as ether and chloroform.
UseIt is suitable for adjuvant treatment of fatty liver, cranial nerve diseases and atherosclerosis.

CTP - Upstream Downstream Industry

Raw MaterialsCelite
D(+)-Glucose
Potassium Phosphate Monobasic
Trichloroacetic acid
Cation exchange resin,strong acidic styrene
Anion exchange resin,strong basic quarternary ammoniumⅠ
Downstream Productsguanosine 5'-(tetrahydrogen triphosphate)

CTP - Nature

epa substance information Cytidine 5'-(tetrahydrogen triphosphate)(65-47-4)
Last Update:2024-04-10 22:29:15

CTP - Production method

Fermentation with CTP as raw material
Fermentation and protein removal take 6.5kg of potassium dihydrogen phosphate, add appropriate amount of water to dissolve, add 0.6kg of magnesium chloride and 17.5kg of glucose, stir to dissolve it, take 2.5kg of CMP2.5kg and add water to dissolve it, adjust pH = 7 with sodium hydroxide, add water to 70L, heat to 50-60 ℃ under stirring, add 180L of yeast solution, keep 30-32 ℃ for 3h, add hydrochloric acid to adjust pH =. Add trichloroacetic acid, adjust pH = 2.5, centrifuge to obtain clear liquid.
CMP [yeast] & rarr;[30-32 ℃, 3h] fermentation broth [trichloroacetic acid] & rarr;[pH2.5] supernatant
Salt removal, precipitation and purification Add the clear liquid to strongly acidic styrene cation exchange resin (001 × 7), stir and adsorb for 15min, make the pH be 1.5-1.7, let stand for 30min, filter, add ethanol to the filtrate to the concentration of alcohol be 75%, let stand overnight, filter, add water to dissolve the filter cake to make the concentration be 25%, add diatomite 1/5 the volume of the filter cake, stir and filter, and collect.
Supernatant [001 × 7 resin] & rarr;[pH1.5-1.7, 15min] filtrate [ethanol] & rarr;[8h] sediment [water, diatomaceous earth] & rarr;[stirring, filtering] filtrate
Adsorption, elution and decolorization: dilute the filtrate with water to a solution of 0.5%-0.6%, adjust Ph = 2-2.5, adsorb with strong alkaline quaternary ammonium type I anion exchange resin (717), wash with water for 8 hours, and then elute ADP with 0.03mol/L sodium chloride solution of pH 2. When the absorbance of the solution at the wavelength of 280nm is greater than 0.4, wash with water at pH2 for 4 hours, finally elute ATP with 1mol/L sodium chloride solution at pH2, add 1‰ amount of activated carbon to the eluent, stir, decolorize, filter and collect filtrate.
Filtrate [717 resin] & rarr;[pH2-2.5] adsorbate [sodium chloride] & rarr;[pH2] elution [activated carbon] & rarr;[40min] filtrate
Precipitate and dry filtrate adjusted Ph = 3-5, add 3 times the amount of ethanol, stand, filter, wash the filter cake with anhydrous ethanol and anhydrous ether, vacuum drying, that is, cytidine disodium triphosphate.
Filtrate [ethanol] & rarr;[pH3.5] precipitate [anhydrous ethanol, anhydrous ether] & rarr; Cytidine disodium triphosphate.

Last Update:2024-04-10 22:29:15
CTP
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 65-47-4
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Cytidine 5'-(tetrahydrogen triphosphate) Visit Supplier Webpage Request for quotation
CAS: 65-47-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: CTP Request for quotation
CAS: 65-47-4
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Cytidine5'-(tetrahydrogentriphosphate) Request for quotation
CAS: 65-47-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Cytidine-5'-triphosphate Visit Supplier Webpage Request for quotation
CAS: 65-47-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Cytidine-5'-triphosphate Visit Supplier Webpage Request for quotation
CAS: 65-47-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: CTP Visit Supplier Webpage Request for quotation
CAS: 65-47-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
CTP
Raw Materials for CTP
Celite
D(+)-Glucose
Potassium Phosphate Monobasic
Trichloroacetic acid
Cation exchange resin,strong acidic styrene
Anion exchange resin,strong basic quarternary ammoniumⅠ
Downstream Products for CTP
guanosine 5'-(tetrahydrogen triphosphate)
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