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Cefoxitin

Cefoxitin

CAS: 35607-66-0

Molecular Formula: C16H17N3O7S2

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Cefoxitin - Names and Identifiers

Name Cefoxitin
Synonyms cfx
Mefoxin
CEFOXITIN
Cefoxitin
cephoxitin
Cefoxitin Acid
CEFOXITIN ACID
(6r-cis)-ethyl)-7-methoxy-8-oxo-7-((2-thienylacetyl)amino)
(6R-cis)-3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7S)-3-[(carbamoyloxy)methyl]-7-methoxy-8-oxo-7-[(thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefoxitin【(6R-cis)-3-[(Carbamoyloxy)methyl]-7-methoxy-8-oxo-7-(2-thienylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid】
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-, (6R,7S)-
CAS 35607-66-0
EINECS 252-641-2
InChI InChI=1/C16H17N3O7S2/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22)/t14?,16-/m0/s1

Cefoxitin - Physico-chemical Properties

Molecular FormulaC16H17N3O7S2
Molar Mass427.45
Density1.4441 (rough estimate)
Melting Point149-150℃
Boling Point843℃
Flash Point>110°(230°F)
Water SolubilityPredicted solubility in water is less than 0.2mg/ml
Solubility DMSO (Slightly), Methanol (Slightly)
Vapor Presure3.24E-30mmHg at 25°C
AppearanceWhite to yellow powder
ColorWhite to Off-White
pKa2.2(at 25℃)
Storage Condition2-8°C
Refractive Index1.6390 (estimate)
In vitro study Cefoxitin has good activity against Gram-positive bacteria. The MICs for several Gram-positive pathogens are in the range of 1-6 μg/mL. Cefoxitin exhibits high efficacy killing B. burgdorferi at concentration of 1.25 µM/mL.

Cefoxitin - Risk and Safety

UN IDs3077
RTECSXI0386500
HS Code30032013
Hazard Class9
Packing GroupIII

Cefoxitin - Reference

Reference
Show more
1. [IF=2.15] Shizhou Wu et al."Antisense yycG Regulation of Antibiotic Sensitivity of Methicillin-Resistant Staphylococcus aureus in Chronic Osteomyelitis."Surg Infect. 2019 Aug;20(6):472-479
Cefoxitin
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Shanghai Yuanye Bio-Technology Co., Ltd.
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CAS: 35607-66-0
Tel: 18301782025
Email: 3008007409@qq.com
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Cefoxitin
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