Chlorfluazuron
Chlorfluazuron
CAS: 71422-67-8
Molecular Formula: C20H9Cl3F5N3O3
Chlorfluazuron - Names and Identifiers
Chlorfluazuron - Physico-chemical Properties
| Molecular Formula | C20H9Cl3F5N3O3 |
| Molar Mass | 540.65 |
| Density | 1.5919 (estimate) |
| Melting Point | approximate 220℃ |
| Water Solubility | ＜0.01mg l-1(20 °C) |
| Vapor Presure | <1 xl0-5 mPa (20 °C) |
| Appearance | neat |
| BRN | 8369967 |
| pKa | 8.10 (acid) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.597 |
| Physical and Chemical Properties | The pure product is White without odor crystal. m.p.232 -233.5 °c, relative density 1.4977(20 °c), vapor pressure <1X10-10Pa(20 °c). Dissolution: cyclohexanone 110g/L, acetone 52.1g/L, ethyl acetate 45.7g/L, dichloroethane 22g/L, toluene 6.5g/L, xylene 3g/L, methanol 2.5 (2.2)g/L, ethanol 2.0g/L, n-octanol 1g/L, hexane 10mg/L, water 0.016mg/L. Stable storage at room temperature, stable to light. The original drug is yellow-brown crystal, melting point 220~223.9 ℃. |
Chlorfluazuron - Risk and Safety
| UN IDs | 3077 |
| WGK Germany | 3 |
| RTECS | CV3459580 |
| Hazard Class | 9 |
| Packing Group | III |
Chlorfluazuron - Nature
Open Data Verified Data
pure white odorless crystals. The melting point is 232~233.5 ℃, the relative density (20 ℃) is 1. 4977, and the vapor pressure (20 ℃) is <1 × l0-10. Solubility in organic solvents (g/L): cyclohexanone 110, acetone 52.1, ethyl acetate 45.7, dichloroethane 22, toluene, xylene, methanol 2.5, ethanol 2.0, octanol, hexane, solubility in water 0.016 mg/L. Stable storage at room temperature, stable to light. The original drug is yellow-brown crystal with melting point of 220-223.9 ℃.
Last Update：2025-06-10 22:55:16
Chlorfluazuron - Preparation Method
Open Data Verified Data
with 2,6 A two chlorobenzonitrile as raw material, potassium fluoride as fluorinating agent, reaction 2,6-= fluorobenzonitrile. It is also possible to prepare each 2,6-fluorobenzonitrile by using a quaternary ammonium salt, a quaternary phosphorus Salt, a crown ether, a polyether or the like as a phase transfer catalyst. The nucleophilic addition reaction of 2,6-= fluorobenzonitrile with water is then carried out in the presence of sulfuric acid as a catalyst to give the corresponding salt, which is treated to give 2,6-= fluorobenzamide. This compound reacts with phosgene to give 2,6-= fluorobenzoyl isocyanate, then with 4-(3 monochloro-5-fluoromethylpyridin-2-oxy) A 3.5 dichloroaniline role in the preparation of fluorouracil urea.
Last Update：2025-06-10 22:55:16
Chlorfluazuron - Application
Open Data Verified Data
benzoylurea insect growth regulators. Broad-spectrum insecticides, mainly gastric toxicity, with strong Contact killing effect, poor permeability, no absorption effect. Can inhibit the formation of chitin, hinder the normal molting of pests, so that the larvae molting, pupa development deformity, and adult eclosion, oviposition blocked, so as to achieve the effect of insecticidal. It is effective for a variety of lepidopteran pests and Diptera, Orthoptera, Hymenoptera pests. Can also be used for cabbage, cotton, tea tree, fruit tree of a variety of pests.
Last Update：2025-08-19 16:24:40
Chlorfluazuron - Safety
Open Data Verified Data
rat oral LD50 was 8500mg/kg, mouse was 7000mg/kg; Rat percutaneous LD50 was lOOOmg/kg; Rat inhaled LCso was 1846mg/m3. No irritation to eyes and skin of rabbits. Guinea pig sensitization test was negative. The subacute oral no-effect dose in rats was 3 mg/kg per day, the subacute percutaneous no-effect dose in rabbits was lOOOmg/kg per day, and the chronic oral no-effect dose in rats was 50mg/kg. Under the experimental conditions, no teratogenic, carcinogenic or mutagenic effect was found. It is safe to birds and bees, and sensitive to silkworm.
Last Update：2022-01-01 10:11:36
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