Conessine
Conessine
CAS: 546-06-5
Molecular Formula: C24H40N2
Conessine - Names and Identifiers
| Name | Conessine |
| Synonyms | NERIINE NERVINE WRIGHTINE Conessine ROGUESSINE n,18-dihydrotrimethyl-conkurchin 3-beta-(dimethylamino)-con-5-enin n-dimethyl-(3-beta)-con-5-enin-3-amin |
| CAS | 546-06-5 |
| EINECS | 208-897-2 |
Conessine - Physico-chemical Properties
| Molecular Formula | C24H40N2 |
| Molar Mass | 356.59 |
| Density | 0.9492 (rough estimate) |
| Melting Point | 126-127°C |
| Boling Point | 479.38°C (rough estimate) |
| Specific Rotation(α) | D20 +25.3° (c = 0.7 in abs alc) |
| Solubility | ethanol: ≥2mg/mL |
| Appearance | powder,white to tan |
| Color | white to tan |
| pKa | 10.20±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | Sensitive to oxides |
| Refractive Index | 1.5640 (estimate) |
Conessine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | GK7621000 |
Conessine - Introduction
Conessine, also known as Conessine, is a natural alkaloid commonly used as one of the active ingredients in Chinese herbal medicine.
The chemical structure of Conessine is C23H26N2O, which is a white crystalline solid, almost insoluble in water, but soluble in organic solvents such as ethanol and ether. It has a bitter taste and a melting point of about 218-220 ° C.
Conessine has a variety of pharmacological and biological activities. It has been found to have a variety of pharmacological effects such as anti-inflammatory, antibacterial, anti-tumor and analgesic. Therefore, in traditional Chinese medicine is widely used in the treatment of rheumatism, diabetes, hepatitis and liver fibrosis and other diseases.
The preparation method of Conessine is mainly extracted from the root of ground hemp. The hemp root is first ground into powder, then extracted with an organic solvent such as ethanol, filtered to remove impurities, and finally purified by distillation and crystallization to obtain Conessine.
Regarding safety information, Conessine is currently considered to have low toxicity, but it still needs to be used with caution. Long-term or excessive use may cause some adverse reactions, such as dizziness, nausea and gastrointestinal discomfort. In addition, Conessine may have effects on pregnant and lactating women, so it needs to be used with caution in these situations. It is best to consult a doctor or pharmacist for advice before use.
The chemical structure of Conessine is C23H26N2O, which is a white crystalline solid, almost insoluble in water, but soluble in organic solvents such as ethanol and ether. It has a bitter taste and a melting point of about 218-220 ° C.
Conessine has a variety of pharmacological and biological activities. It has been found to have a variety of pharmacological effects such as anti-inflammatory, antibacterial, anti-tumor and analgesic. Therefore, in traditional Chinese medicine is widely used in the treatment of rheumatism, diabetes, hepatitis and liver fibrosis and other diseases.
The preparation method of Conessine is mainly extracted from the root of ground hemp. The hemp root is first ground into powder, then extracted with an organic solvent such as ethanol, filtered to remove impurities, and finally purified by distillation and crystallization to obtain Conessine.
Regarding safety information, Conessine is currently considered to have low toxicity, but it still needs to be used with caution. Long-term or excessive use may cause some adverse reactions, such as dizziness, nausea and gastrointestinal discomfort. In addition, Conessine may have effects on pregnant and lactating women, so it needs to be used with caution in these situations. It is best to consult a doctor or pharmacist for advice before use.
Last Update：2024-04-09 20:52:54
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