Demethyleneberberine
Demethyleneberberine
CAS: 25459-91-0
Molecular Formula: C19H18NO4+
Demethyleneberberine - Names and Identifiers
Demethyleneberberine - Physico-chemical Properties
| Molecular Formula | C19H18NO4+ |
| Molar Mass | 324.36 |
| Solubility | Soluble in water, hardly soluble in benzene, ether and chloroform. |
| Appearance | Yellow crystal |
| Storage Condition | 2-8℃ |
| MDL | MFCD22417296 |
| Physical and Chemical Properties | Yellow crystal, soluble in methanol, ethanol, DMSO and other organic solvents, from Phellodendron amurense. |
Demethyleneberberine - Reference
| Reference Show more | 1. Wang, Kun, et al. "Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry." Journal of pharmaceutical and biomedical analysis 139 (2017): 73-86.https://doi.org/10.1016/ 2. Zhu, Jianzhong, et al. "In-vitro inhibitory effects of flavonoids in Rosa roxburghii and R. sterilis fruits on α-glucosidase: Effect of stomach digestion on flavonoids alone and in combination with acarbose." Journal of Functional Foods 54 (2019): 13-21.ht 3. [IF=3.935] Kun Wang et al."Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry."J Pharmaceut Biomed. 2017 May;139:73 4. [IF=6.4] Jing Zhao et al."Natural Nano-Drug Delivery System in Coptidis Rhizoma Extract with Modified Berberine Hydrochloride Pharmacokinetics."Int J Nanomed. 2021; 16: 6297–6311 5. [IF=5.81] Zhao Jing et al."Intra-Herb Interactions: Primary Metabolites in Coptidis Rhizoma Extract Improved the Pharmacokinetics of Oral Berberine Hydrochloride in Mice."Front Pharmacol. 2021 Jun;0:1426 6. [IF=5.81] Xinchi Feng et al."Pharmacokinetics and Excretion of Berberine and Its Nine Metabolites in Rats."Front Pharmacol. 2020; 11: 594852 7. [IF=1.902] Xinchi Feng et al."Systematic screening and characterization of absorbed constituents and in vivo metabolites in rats after oral administration of Rhizoma coptidis using UPLC-Q-TOF/MS."Biomed Chromatogr. 2020 Oct;34(10):e4919 |
Demethyleneberberine - Introduction
Methylberberine is a natural alkaloid found mainly in certain plants in Asia, such as Berberis. The following is an introduction to the properties, uses, preparation methods and safety information of methylene berberine:
Nature:
-Methylene Berberine is a white crystalline powder with a bitter taste, soluble in organic solvents such as ethanol, chloroform and ether, and slightly soluble in water.
-it belongs to alkaloid compounds, with antibacterial, anti-inflammatory, antioxidant and other pharmacological activity.
Use:
-Methylene Berberine is widely used in the field of medicine. It has the ability to inhibit the growth of bacteria and fungi and is often used in the preparation of antibacterial and antifungal drugs.
-In addition, methylene berberine also has anti-inflammatory, antioxidant and anti-inflammatory effects, so it is also used in dermatological drugs, cosmetics and oral care products.
Preparation Method:
-Methylene Berberine is usually obtained by extraction or synthesis from Berberis plants.
-The extraction method includes extraction and separation and purification from the stem and leaf parts of the plant.
-Synthetic methods require chemical synthesis techniques and appropriate raw materials.
Safety Information:
-Methylene Berberine is a natural product, but when using it, you still need to comply with the corresponding safety operating regulations, avoid contact with skin and eyes, and avoid intake.
-Although methylene Berberine is widely used in drugs and cosmetics, if discomfort or adverse reactions such as allergies occur during use, it should be stopped immediately, and consult a doctor's advice.
Please note that the specific properties, uses, preparation methods and safety information of methylene berberine may vary depending on the specific product. It is recommended to read the product manual carefully before use, follow manufacturer's guidance and recommendations.
Nature:
-Methylene Berberine is a white crystalline powder with a bitter taste, soluble in organic solvents such as ethanol, chloroform and ether, and slightly soluble in water.
-it belongs to alkaloid compounds, with antibacterial, anti-inflammatory, antioxidant and other pharmacological activity.
Use:
-Methylene Berberine is widely used in the field of medicine. It has the ability to inhibit the growth of bacteria and fungi and is often used in the preparation of antibacterial and antifungal drugs.
-In addition, methylene berberine also has anti-inflammatory, antioxidant and anti-inflammatory effects, so it is also used in dermatological drugs, cosmetics and oral care products.
Preparation Method:
-Methylene Berberine is usually obtained by extraction or synthesis from Berberis plants.
-The extraction method includes extraction and separation and purification from the stem and leaf parts of the plant.
-Synthetic methods require chemical synthesis techniques and appropriate raw materials.
Safety Information:
-Methylene Berberine is a natural product, but when using it, you still need to comply with the corresponding safety operating regulations, avoid contact with skin and eyes, and avoid intake.
-Although methylene Berberine is widely used in drugs and cosmetics, if discomfort or adverse reactions such as allergies occur during use, it should be stopped immediately, and consult a doctor's advice.
Please note that the specific properties, uses, preparation methods and safety information of methylene berberine may vary depending on the specific product. It is recommended to read the product manual carefully before use, follow manufacturer's guidance and recommendations.
Last Update：2024-04-09 15:16:35
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