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Dexmedetomidine

Dexmedetomidine

CAS: 113775-47-6

Molecular Formula: C13H16N2

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Dexmedetomidine - Names and Identifiers

Name Dexmedetomidine
Synonyms MPV 1440
Precedex
d-Medetomidine
Dexmedetomidine
UNII-67VB76HONO
Dexmedetomidina
(S)-Medetomidine
Dexmedetomidinum
Dexmedetomidinum [INN-Latin]
Dexmedetomidina [INN-Spanish]
Dexmedetomidinehclc13H16N2.Hcl
DexmedetomidineHclC13H16N2.Hcl
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
5-[(1R)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
Dexmedetomidine Hcl C13H16N2.Hcl 145108-58-3(Hcl)
1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-, (R)-
(+)-4-[(S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
CAS 113775-47-6
EINECS 601-281-8
InChI InChI=1/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1

Dexmedetomidine - Physico-chemical Properties

Molecular FormulaC13H16N2
Molar Mass200.28
Density1.053±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point146-149°C
Boling Point381.9±11.0 °C(Predicted)
Flash Point191.3°C
Vapor Presure1.08E-05mmHg at 25°C
pKa13.89±0.10(Predicted)
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.569
In vitro studyDexmedetomidine has a relatively high ratio of α2/α1-activity (1620:1, compared to 220:1 for clonidine) and is therefore considered to be a full agonist of the α2 receptor. This may lead to more effective sedation without the cardiovascular response caused by the activation of redundant α1 receptors. The 2-hour half-life of Dexmedetomidine is almost 4 times shorter than that of clonidine, which increases the possibility that continuous administration of dexmedetomidine is effective for sedation. Dexmedetomidine also has minimal alveolar anesthetic concentration (MAC)-retention properties, but its use as an anesthetic is complicated by persistent hypotension, intravenous infusion administration and vasopressor administration. In addition, its use in large doses is accompanied by a2-receptor mediated vasoconstriction caused by hypertension.
Dexmedetomidine
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SKYRUN INDUSTRIAL CO.,LTD
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Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: Dexmedetomidine Request for quotation
CAS: 113775-47-6
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
Shanghai Amole Biotechnology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Dexmedetomidine Request for quotation
CAS: 113775-47-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Dexmedetomidine Visit Supplier Webpage Request for quotation
CAS: 113775-47-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: (+)-Medetomidine; (S)-Medetomidine Visit Supplier Webpage Request for quotation
CAS: 113775-47-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: DexmedetomidineHclC13H16N2.Hcl Visit Supplier Webpage Request for quotation
CAS: 113775-47-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
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View History
Dexmedetomidine
3209-30-1
1094-61-7
18368-63-3
598-02-7
1611-92-3
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