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Diethyl(phenylacetyl)malonate

Diethyl(phenylacetyl)malonate

CAS: 20320-59-6

Molecular Formula: C15H18O5

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Diethyl(phenylacetyl)malonate - Names and Identifiers

Name Diethyl(phenylacetyl)malonate
Synonyms NEW BMK POWDER
NEW BMK OIL BMK LIQUID
Diethyl(phenylacetyl)malonate
diethyl 2-(2-phenylacetyl)propanedioate
Propanedioic acid, (phenylacetyl)-, diethyl ester
diethyl 2-(2-phenylacetyl)propanedioate wickr bettyml
Propanedioic acid, 2-(2-phenylacetyl)-, 1,3-diethyl ester
Pharmaceutical intermediates Diethyl(phenylacetyl)malonate
BMK
CAS 20320-59-6
EINECS 205-854-1

Diethyl(phenylacetyl)malonate - Physico-chemical Properties

Molecular FormulaC15H18O5
Molar Mass278.3
Density1.148±0.06 g/cm3(Predicted)
Boling Point120 °C(Press: 0.01 Torr)
pKa8.76±0.59(Predicted)
UseIntermediates in organic synthesis.

Diethyl(phenylacetyl)malonate - Production method

Diethyl phthalate and sodium metal co-steamed anhydrous ethanol, drop to the mixture of diethyl malonate, carbon tetrachloride and magnesium, heat to start the reaction, control the temperature to make the reaction smooth. Then add anhydrous ether, heat for 1h, and add the ether solution of phenylacetyl chloride (slowly add, do not make the reaction too intense). After the reaction, cool and add water to separate the oil layer, evaporate the ether under reduced pressure to obtain diethyl phenyllevulonate.

Last Update:2024-04-10 22:29:15

Diethyl(phenylacetyl)malonate - Production method

Diethyl phthalate and sodium metal co-steamed anhydrous ethanol, drop to the mixture of diethyl malonate, carbon tetrachloride and magnesium, heat to start the reaction, control the temperature to make the reaction smooth. Then add anhydrous ether, heat for 1h, and add the ether solution of phenylacetyl chloride (slowly add, do not make the reaction too intense). After the reaction, cool and add water to separate the oil layer, evaporate the ether under reduced pressure to obtain diethyl phenyllevulonate.

Last Update:2024-04-10 22:29:15
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Diethyl(phenylacetyl)malonate
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HIS(DEAMINO)-OH
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