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ENT-3

(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane

CAS: 110567-22-1

Molecular Formula: C20H22O3

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ENT-3 - Names and Identifiers

Name (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane
Synonyms ENT-3
Entecavir intermediate 3
Entecavir intermediate N3
1R,2R-2-[(Phenylmethoxy)methyl]-3-cyclopenten-1-ol
(1S,2R,3S,5R)-3-(Benzyloxymethyl)-6-oxabicyclo[3.1.0]hexane
(1S,2R,3S,5R)-3-(benzyloxy)-2-[(benzyloxy)methyl]-6-oxabicyclo[3.1.0]hexane
(1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane
(1S,2R,3S,5R)-3-(benzyloxy)-2-((4-methylbenzyloxy)methyl)-6-oxabicyclo[3.1.0]hexane
(1S,2R,3S,5R)-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane
[1S-(1a,2a,3,5a)]-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane
[1S-(1α,2α,3β,5α)]-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane
6-Oxabicyclo[3.1.0]hexane, 3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S, 2R, 3S, 5R)
CAS 110567-22-1
EINECS 1592732-453-0
InChI InChI=1/C20H22O3/c1-3-7-15(8-4-1)12-21-14-17-18(11-19-20(17)23-19)22-13-16-9-5-2-6-10-16/h1-10,17-20H,11-14H2/t17-,18+,19-,20+/m1/s1

ENT-3 - Physico-chemical Properties

Molecular FormulaC20H22O3
Molar Mass310.39
Density1.17
Boling Point427.9±40.0 °C(Predicted)
Flash Point145.852°C
Solubility Benzene, Chloroform, DMSO, Methanol
Vapor Presure0mmHg at 25°C
AppearanceOil
ColorColorless to Pale Yellow
Storage ConditionSealed in dry,2-8°C
Refractive Index1.593

ENT-3 - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
HS Code29329990

ENT-3 - Introduction

(1S,2R,3S,5R)-3-(benzyloxy)-2-[(benzyloxy) methyl]-6-oxabicyclo [3.1.0] hexane is an organic compound also known as 1,2, 3,5-tetraoxabicyclo [3.1.0] hexane.

Nature:
-Appearance: colorless liquid
-Molecular formula: C14H18O3
-Molecular weight: 234.29g/mol

Use:
(1S,2R,3S,5R)-3-(benzyloxy)-2-[(benzyloxy) methyl]-6-oxabicyclo [3.1.0] hexane has important application value in the field of drugs, and is often used as a synthetic intermediate of hypnotics, anxiolytics and antiepileptic drugs.

Preparation Method: The preparation method of
(1S,2R,3S,5R)-3-(benzyloxy)-2-[(benzyloxy) methyl]-6-oxabicyclo [3.1.0] hexane is complicated, and a common synthetic route is to obtain the target product through a ring-closing reaction. The specific synthetic steps vary depending on factors such as reaction conditions and configuration.

Safety Information:
At present, the safety and toxicity of the compound are limited, so we should pay attention to the correct operation and laboratory safety. Wear personal protective equipment such as goggles, gloves, and protective clothing when using or handling the compound. At the same time, pay attention to avoid inhalation, intake and contact with skin. Dispose of waste and solvents generated during operation and comply with local codes and regulations. To ensure safety, please refer to the relevant safety data sheet (MSDS) of the chemical.
Last Update:2024-04-09 21:11:58
ENT-3
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View History
ENT-3
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