| Molecular Formula | C25H30N6O2 |
| Molar Mass | 446.5447 |
| Density | 1.20±0.1 g/cm3(Predicted) |
| Melting Point | 136-140°C |
| Boling Point | 662.3±55.0 °C(Predicted) |
| Solubility | DMSO: ≥ 33 mg/mL |
| Appearance | Form Solid, Color Yellow |
| pKa | 9.45±0.29(Predicted) |
| Storage Condition | -20°C Freezer, Under inert atmosphere |
| Physical and Chemical Properties | Bioactive Erdafitinib (JNJ-42756493) is an effective, selective and oral biologically active panfibroblast growth factor receptor FGFR inhibitor with potential anti-tumor activity. Erdafitinib can also combine RET (c-RET), CSF-1R, PDGFR-α/PDGFR-β, FLT4, Kit (c-Kit) and VEGFR-2 and induce apoptosis. |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.239 ml | 11.197 ml | 22.394 ml |
| 5 mM | 0.448 ml | 2.239 ml | 4.479 ml |
| 10 mM | 0.224 ml | 1.12 ml | 2.239 ml |
| 5 mM | 0.045 ml | 0.224 ml | 0.448 ml |