FLUSPIRILENE
FLUSPIRILENE
CAS: 1841-19-6
Molecular Formula: C29H31F2N3O
FLUSPIRILENE - Names and Identifiers
FLUSPIRILENE - Physico-chemical Properties
| Molecular Formula | C29H31F2N3O |
| Molar Mass | 475.57 |
| Density | 1.1634 (estimate) |
| Melting Point | 187.5-190° |
| Boling Point | 668.9±55.0 °C(Predicted) |
| Solubility | DMSO: soluble |
| Appearance | amorphous solid |
| Color | white to yellow |
| pKa | 15.05±0.20(Predicted) |
| Storage Condition | room temp |
| In vitro study | Fluspirilene, at concentrations which non-competitively modify dihydropyridine binding, selectively antagonizes the effects of calcium-channel activators. Fluspirilene decreases the viability and suppresses sphere-forming of glioma stem cell lines in a dose-dependent manner. Fluspirilene demonstrates the inhibition of proliferation of T98, U87 and all GSC lines at 1.25, 2.5, and 5 μM, while it inhibits the proliferation of U251 and SNB19 at 2.5 and 5 μM. |
| In vivo study | Mice treated with fluspirilene shows a remarkable reduction of the tumor size. Fluspirilene significantly prolongs survival of the TGS04 mouse model. |
FLUSPIRILENE - Risk and Safety
| UN IDs | 3249 |
| WGK Germany | 3 |
| RTECS | XX8750000 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 i.m. in rats: 146 ±14 mg/kg (Janssen) |
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Product Name: R 6218; Redeptin Visit Supplier Webpage Request for quotationCAS: 1841-19-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: FLUSPIRILENE Visit Supplier Webpage Request for quotation
CAS: 1841-19-6
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Email: 3008007409@qq.com
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QQ: 3008007409
CAS: 1841-19-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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