Flavone
Flavone
CAS: 525-82-6
Molecular Formula: C15H10O2
Flavone - Names and Identifiers
| Name | Flavone |
| Synonyms | DA6034 Flavon Flavone Cromaril Phenylchromone 2-Phenylchromone 2-Phenyl-γ-benzopyrone Flavone(2-Phenylchromone) 2-phenyl-4H-chromen-4-one 2-Phenyl-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one,2-phenyl- 4H-1-Benzopyran-4-one, 2-phenyl- |
| CAS | 525-82-6 |
| EINECS | 208-383-8 |
| InChI | InChI=1/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H |
Flavone - Physico-chemical Properties
| Molecular Formula | C15H10O2 |
| Molar Mass | 222.24 |
| Density | 1.1404 (rough estimate) |
| Melting Point | 94-97 °C (lit.) |
| Boling Point | 185 °C / 1mmHg |
| Flash Point | 171.1°C |
| Water Solubility | Soluble in acetone (25 mg/ml), methanol, alcohol, and chloroform. Insoluble in water. |
| Solubility | Soluble in ethanol, benzene and chloroform, slightly soluble in ether, almost insoluble in water |
| Vapor Presure | 1.41E-05mmHg at 25°C |
| Appearance | Powder |
| Color | White |
| Merck | 14,4092 |
| BRN | 157598 |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.6600 (estimate) |
| MDL | MFCD00006825 |
Flavone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 2 |
| RTECS | DJ3100630 |
| TSCA | Yes |
| HS Code | 29329990 |
| Hazard Note | Irritant |
Flavone - Reference
| Reference Show more | 1. [IF=5.279] Qinggang Yin et al."Identification of Specific Glycosyltransferases Involved in Flavonol Glucoside Biosynthesis in Ginseng Using Integrative Metabolite Profiles, DIA Proteomics, and Phylogenetic Analysis."J Agr Food Chem. 2021;69(5):1714–1726 2. [IF=4.556] Jinjie Hua et al."Effects of novel fermentation method on the biochemical components change and quality formation of Congou black tea."J Food Compos Anal. 2021 Mar;96:103751 |
Flavone - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | flavonoids are widely found in some plants and berries in nature. many traditional Chinese medicines also contain flavonoids. scientists have found that ginkgo trees, known as living fossils, contain relatively more flavonoids, which can be extracted from ginkgo leaves. Flavonoids have anti-inflammatory properties, and also prevent the growth and reproduction of pathogenic microorganisms in the body. |
| effect | flavonoids can improve blood circulation and reduce cholesterol. flavonoids also contain a PAF anticoagulant factor, which greatly reduces the incidence of cardiovascular and cerebrovascular diseases. It can also improve the symptoms of cardiovascular and cerebrovascular diseases. Flavonoids have a regulatory effect on blood pressure, blood sugar and blood lipids. Flavonoids relieve alcohol and protect liver, prevent osteoporosis and improve immunity; Effectively treat constipation. Flavonoids have a magical effect on lowering blood sugar, but more importantly, it has a good effect on stabilizing collagen, so it has a good effect on retinopathy and capillary embrittlement caused by diabetes. flavonoids can inhibit the exudation of inflammatory biological enzymes, can improve wound healing and pain relief, Quercus has strong anti histamine, can be used for all kinds of sensitive diseases. |
| metabolism | first: flavonoids entering the intestine can interact with the intestinal flora and are metabolized into aromatic acids or phenolic acids, or can bind to intestinal epithelial cells. For example, quercetin can prevent the growth and reproduction of some microorganisms in the body such as rumen cocci and lactic acid bacteria. Of course, flavonoids can also promote the growth and reproduction of specific flora. For example, flavonoids in apples can promote the content of Bifidobacteria and reduce the content of lactic acid bacteria. Second: Flavonoids act on intestinal contents, which can protect intestinal epithelial cells from drugs and food toxins, regulate the enzyme activity of lipid and carbohydrate absorption and metabolism, and maintain the integrity of intestinal barrier. Third, it can regulate the secretion of intestinal hormones, adjust the gastrointestinal immune system, and play a potential anti-cancer effect. |
| biological activity | Flavone is an endogenous metabolite. |
Last Update：2024-04-09 20:45:29
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