Fmoc-Phe-ol
Fmoc-Phe-ol
CAS: 129397-83-7
Molecular Formula: C24H23NO3
Fmoc-Phe-ol - Names and Identifiers
| Name | Fmoc-Phe-ol |
| Synonyms | FMOC-PHE-OL Fmoc-Phe-ol FMOC-PHENYLALANINOL Fmoc-Phenylalaninol Fmoc-L-Phenylalaninol FMOC-L-PHENYLALANINOL Fmoc-DL-Phenylalaninol Fmoc-Dl-Phenylalaninol N-Fmoc-L-Phenylalaninol N-FMOC-L-PHENYLALANINOL N-ALPHA-FMOC-L-PHENYLALANINOL N-Alpha-Fmoc-L-Phenylalaninol FMOC-(S)-2-AMINO-3-PHENYL-1-PROPANOL Fmoc-(S)-2-Amino-3-Phenyl-1-Propanol N-(9-FLUORENYLMETHOXYCARBONYL)-L-PHENYLALANINOL N-(9-Fluorenylmethoxycarbonyl)-L-Phenylalaninol 9H-Fluoren-9-Ylmethyl [(1S)-1-Benzyl-2-Hydroxyethyl]Carbamate (S)-(9H-Fluoren-9-Yl)Methyl 1-Hydroxy-3-Phenylpropan-2-Ylcar |
| CAS | 129397-83-7 |
| InChI | InChI=1/C24H23NO3/c26-15-18(14-17-8-2-1-3-9-17)25-24(27)28-16-23-21-12-6-4-10-19(21)20-11-5-7-13-22(20)23/h1-13,18,23,26H,14-16H2,(H,25,27)/t18-/m0/s1 |
Fmoc-Phe-ol - Physico-chemical Properties
| Molecular Formula | C24H23NO3 |
| Molar Mass | 373.44 |
| Density | 1.219±0.06 g/cm3(Predicted) |
| Melting Point | 129-130 °C |
| Boling Point | 606.1±50.0 °C(Predicted) |
| Flash Point | 320.4°C |
| Vapor Presure | 1.52E-15mmHg at 25°C |
| Appearance | Solid |
| pKa | 11.44±0.46(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.625 |
| MDL | MFCD00235941 |
| Physical and Chemical Properties | Storage Conditions:-15 ℃ |
Fmoc-Phe-ol - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29051990 |
| Hazard Class | IRRITANT |
Fmoc-Phe-ol - Introduction
(S)-N-FMOC phenylalaninol is a common organic synthesis intermediate. Its structure contains an FMOC (9-fluororenylformylaminocarbonyl) protecting group and a phenylalaninol group.
Nature:
(s)-N-FMOC phenylalaninol is a white crystalline solid with a relatively high melting and boiling point. It is less soluble in water, but better soluble in organic solvents.
Use:
In organic synthesis,(s)-N-FMOC phenylalaninol is often used as a chiral inducer to control the stereoselectivity of chemical reactions. It can be used in the synthesis of chiral drugs, chiral materials and chiral catalysts.
Preparation Method:
A method for preparing (s)-N-FMOC phenylalaninol is through the reaction of amphetamine and FMOC chloroformate. The specific synthesis steps and conditions can be optimized and adjusted according to the needs of the experiment.
Safety Information:
When using and storing (s)-N-FMOC phenylalaninol, care should be taken to avoid contact with strong oxidants and strong acids to prevent dangerous reactions. At the same time, care should be taken to avoid inhalation and contact with skin or eyes to avoid irritation or allergic reactions. Appropriate personal protective equipment such as lab gloves, goggles and laboratory clothing should be worn during operation. In case of accidental inhalation or contact, seek medical attention promptly.
Nature:
(s)-N-FMOC phenylalaninol is a white crystalline solid with a relatively high melting and boiling point. It is less soluble in water, but better soluble in organic solvents.
Use:
In organic synthesis,(s)-N-FMOC phenylalaninol is often used as a chiral inducer to control the stereoselectivity of chemical reactions. It can be used in the synthesis of chiral drugs, chiral materials and chiral catalysts.
Preparation Method:
A method for preparing (s)-N-FMOC phenylalaninol is through the reaction of amphetamine and FMOC chloroformate. The specific synthesis steps and conditions can be optimized and adjusted according to the needs of the experiment.
Safety Information:
When using and storing (s)-N-FMOC phenylalaninol, care should be taken to avoid contact with strong oxidants and strong acids to prevent dangerous reactions. At the same time, care should be taken to avoid inhalation and contact with skin or eyes to avoid irritation or allergic reactions. Appropriate personal protective equipment such as lab gloves, goggles and laboratory clothing should be worn during operation. In case of accidental inhalation or contact, seek medical attention promptly.
Last Update：2024-04-09 21:11:58
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