GLA
Evening primrose oil
CAS: 90028-66-3
Molecular Formula:
GLA - Names and Identifiers
GLA - Physico-chemical Properties
| Density | 0.926 g/mL at 25 °C |
| Flash Point | >110℃ |
| Refractive Index | n20/D1.479 |
GLA - Risk and Safety
| WGK Germany | 3 |
GLA - Study on Prescription of Evening Primrose Oil Self-emulsifying Preparation
From HowNet
Author:
Li Guodong ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(fdc695f6d19e2da4) author:(Fan Wei)" target = "_blank"> Fan Wei ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(77113 d4aac09f181) author:(Lu Guohao)" target = "_blank"> Lu A href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(324 da822f0c0372f) author:(Gao Shen)" target = "_blank"> Gao Shen ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(eeafe3c9620fd2a6) author:(Zhang Yong)" target = "_blank"> Zhang Yong
Summary:
Objective: To study the self-emulsifying preparation of evening primrose oil and explore the best prescription ratio. Methods: Through solubility experiment, orthogonal screening and three-phase diagram drawing, the emulsification degree of emulsion formation, the volume of unemulsified oil and the size of the obtained milk drop particle size were used as indicators to screen the dosage ratio of drugs, non-ionic surfactants and latent solvents in evening primrose oil prescription to find the best matching and prescription ratio. Results: In the prescription of self-emulsifying preparation of evening primrose oil, good emulsifying effect can be obtained when Tween -85 is used as nonionic surfactant and propylene glycol is used as latent solvent. Conclusion: The best prescription ratio for self-emulsification of evening primrose oil is evening primrose oil: Tween-85: propylene glycol -5:7:3.
keywords:
evening primrose oil self-emulsification dosage form improvement
DOI:
10.3321/j.issn:0258-879X.2004.03.027
cited:
Year:
2004
Last Update：2024-01-02 23:10:35
GLA - Therapeutic Effect of Evening Primrose Oil and Polyenecan on Insulin Resistance in Diabetic Rats
From HowNet
Author:
Wang Jiazhen ,< a href = "https://xueshu.baidu.com/usercenter/data/author?cmd=authoruri&wd=authoruri:(50 ebb9a54fd1762c) author:(Wang Xiudi)" target = "_blank"> Wang Xiudi
Summary:
In alloxan-induced diabetic rat model, the effects of evening primrose oil and doenkang on insulin resistance in diabetic rats were observed. The results showed that diabetic rats had severe insulin resistance, which was significantly different from the normal control group (P0.01). The insulin resistance of the two treatment groups was significantly improved, which was significantly different from that of the untreated group (all P0.01).
keywords:
evening primrose oil doenecan insulin resistance diabetes Drug therapy
DOI:
CNKI:SUN:ZJYE. 0.1998-01-017
cited:
Year:
1998
Last Update：2023-08-16 22:23:51
GLA - Evening primrose oil wet towel
from Baidu library
Application (Patent) No.:
CN201611087495.1
date of application:
2016-12-01
public/announcement number:
CN108125822A
date of publication/announcement:
2018.06.08
Applicant (patentee):
Qingdao saize network technology co., ltd
Inventor:
national and provincial code:
CN370213
Summary:
a kind of evening primrose oil wet wipes, belonging to the technical field of daily necessities. The evening primrose oil wet wipes of the present invention comprises: a biodegradable substrate and evening primrose oil liquid. Among them, the biodegradable substrate is woven from cellulose fiber with a weight content of 68% and chitin fiber with a weight content of 32%. Evening primrose oil liquid medicine consists of the following components by weight: 0.050.15 parts of evening primrose essential oil, 0.010.2 parts of citrus essential oil, 0.51.5 parts of lauryl sarcosine isopropyl ester, 0.30.5 parts of cetearyl sodium sulfate, 0.53.5 parts of glycerin and 100 parts. The evening primrose oil wet wipes of the present invention can clean, moisturize, disinfect and sterilize the skin; the base material of the present invention adopts biodegradable antibacterial wet wipes, which not only effectively solves the antibacterial problem of wet wipes, but also relieves the pressure brought to the environment by wet wipes that are not easy to degrade.
Last Update：2023-08-16 22:23:51
GLA - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | evening primrose is a plant that blooms in the evening. this quite unique characteristic made it attract attention a long time ago. In Europe and America, evening primrose oil has a long history of use, usually used to treat eczema, anti-inflammatory, menopausal symptoms, premenstrual syndrome and so on. In modern times, there are still people used to treat cardiovascular diseases, diabetes, asthma and even cancer. Evening primrose is a plant that blooms in the evening. This rather unique characteristic made it a long time ago. In Europe and America, evening primrose oil has a long history of use, usually used to treat eczema, anti-inflammatory, menopausal symptoms, premenstrual syndrome and so on. In modern times, there are still people used to treat cardiovascular diseases, diabetes, asthma and even cancer. |
| main ingredients | natural evening primrose oil is light yellow and contains about 90% unsaturated fatty acids. main ingredients: r-linoleic acid, magnesium, zinc, copper, vitamin c, e, B6, B5. Among them, the most abundant are linoleic acid (Linoleic Acid, LA for short) with a content of about 70% and GLA with a content of about 7 ~ 10%. |
| efficacy indications | activating blood and dredging collaterals; Xifunping liver; detumescence and ulcers. Main chest pain and heartache; stroke hemiplegia; internal movement of deficiency wind; hyperactivity in children; rheumatism and pain; abdominal pain and diarrhea; dysmenorrhea; fox confusion; sores; eczema |
| efficacy and action | evening primrose oil can blend the oil of base oil and essential oil. it has many therapeutic and whitening functions. it can be made into capsules and taken orally to treat cardiovascular diseases, premenstrual syndrome, menopausal syndrome and aromatherapy. it can reconcile lotions and creams, improve eczema and psoriasis, help wound healing, nail development and solve hair problems, generally, the dosage is 10%. Evening primrose oil also has the effects of lowering blood lipids and anti-atherosclerosis, weight loss, anti-fatty liver, anti-arrhythmia, anti-inflammatory effects, etc. |
| mode of action | many benefits of evening primrose oil come from the rich γ-linolenic acid it contains. Therefore, as an unsaturated fatty acid, GLA may also affect the normal operation of receptors, enzymes and ion channels in the human body. |
| application field | evening primrose oil is extracted from evening primrose seeds and is most commonly used as an oral supplement. It also has some other common uses including: • Reduce acne outbreaks. • Relieve multiple symptoms of psoriasis • Reduce neuropathy in diabetic patients. |
| extraction process | evening primrose oil is mainly derived from evening primrose seeds and extracted at low temperature by low temperature pressing or butane mixed solvent. |
| applicable population | adult women with menstrual period, female premenstrual syndrome or menopausal discomfort symptoms need to be supplemented with evening primrose oil; patients with dermatitis, rheumatoid arthritis and multiple sclerosis can be properly supplemented with evening primrose oil; ladies with poor skin condition should be properly supplemented with evening primrose oil. Alcoholics will lack γ-linolenic acid. Many people in Western countries will lack γ-linolenic acid due to age, blood sugar intolerance, high fat intake and other diseases. |
| side effects | evening primrose oil is very safe and has no side effects (about 500-1000 mg of GLA) at normal doses, but there are still very few people suffering from nausea, stomach pain, headache and soft stool symptoms, which may be related to excessive dosage. |
Last Update：2024-04-09 20:52:54
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