H-DAP(BOC)-OME

H-DAP(BOC)-OME - Names and Identifiers

Name	3-[[(1,1-Dimethylethoxy)carbonyl]amino]-L-alanine methyl ester
Synonyms	H-Dap(Boc)-OMe H-L-Dap(Boc)-OMe (S)-methyl 2-amino-3-N-Boc-propanoate Methyl 3-[(tert-butoxycarbonyl)amino]-L-alaninate methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate 3-[[(1,1-DiMethylethoxy)carbonyl]aMino]-L-alanine Ethyl Ester 3-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]-L-ALANINE METHYL ESTER 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-L-alanine methyl ester L-alanine, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester (2S)-2-AMino-3-[(tert-butoxycarbonyl)aMino]propionic Acid Methyl Ester methyl (L)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride
CAS	77087-60-6
InChI	InChI=1/C9H18N2O4/c1-9(2,3)15-8(13)11-5-6(10)7(12)14-4/h6H,5,10H2,1-4H3,(H,11,13)/t6-/m0/s1

H-DAP(BOC)-OME - Physico-chemical Properties

Molecular Formula	C9H18N2O4
Molar Mass	218.25
Density	1.107±0.06 g/cm3(Predicted)
Boling Point	325.7±32.0 °C(Predicted)
Flash Point	150.8°C
Vapor Presure	0.000227mmHg at 25°C
pKa	11.95±0.46(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.463

H-DAP(BOC)-OME - Introduction

Nature:
-Appearance: 3-[[(1,1-dimethylethoxy) carbonyl]amino]-L-alanine methyl ester is a white crystalline solid.
-Solubility: It dissolves well in some organic solvents, such as chloroform and methanol.

Use:
- 3-[[(1,1-dimethylethoxy) carbonyl]amino]-L-alanine methyl ester is often used as one of the starting substances for polypeptide synthesis in organic synthesis, for the synthesis of polypeptides and proteins.
-It is also commonly used as an intermediate for the synthesis of other organic compounds.

Preparation Method:
- 3-[[(1,1-dimethethoxy) carbonyl]amino]-L-alanine methyl ester can be prepared by the following steps:
1. First, the N α-protected amino acid is condensed with diuracilyl propionate.
2. The Phillips reagent (TBDMS:t-butyldimethylsilyl chloride) is then reacted with the condensate to generate an intermediate acyl chloride.
3. finally, methyl esterification of the intermediate product was carried out with methanol and sodium hydroxide to obtain the final product 3-[[(1,1-dimethylethoxy) carbonyl]amino]-L-alanine methyl ester.

Safety Information:
- 3-[[(1,1-dimethethoxy) carbonyl]amino]-L-alanine specific safety information of methyl ester needs to be evaluated and understood according to the relevant material safety data sheet (MSDS).
-Appropriate laboratory safety measures should be taken when handling the compound, including wearing appropriate protective equipment, such as gloves and glasses.
-In addition, ensure that the compound is stored, handled and disposed of in accordance with safe operating procedures.

Last Update：2024-04-09 21:00:56