Harpagosid
Harpagosid
CAS: 19210-12-9
Molecular Formula: C24H30O11
Harpagosid - Names and Identifiers
Harpagosid - Physico-chemical Properties
| Molecular Formula | C24H30O11 |
| Molar Mass | 494.49 |
| Density | 1.52±0.1 g/cm3(Predicted) |
| Melting Point | 120°C (dec.) |
| Boling Point | 720.7±60.0 °C(Predicted) |
| Specific Rotation(α) | (c, 0.19 in CHCl3)-27.7；(c, 0.99 in MeOH)-42.6 |
| Flash Point | 244.3°C |
| Solubility | Soluble in methanol and water |
| Vapor Presure | 8.49E-22mmHg at 25°C |
| Appearance | White powder |
| Color | White to Light Yellow |
| pKa | 11.70±0.70(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Stability | Hygroscopic |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.659 |
| MDL | MFCD00017415 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, water, derived from Scrophulariae, hook fruit grass. |
Harpagosid - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | S22 - Do not breathe dust. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. |
| UN IDs | 3172 |
| WGK Germany | 3 |
| HS Code | 29389090 |
Harpagosid - Reference
| Reference Show more | 1. Cheng Jian, Di Liuqing, Li Junsong et al. Simultaneous Determination of 10 Active Components in Tongsaimai Pellets by UPLC-MS/MS [J]. Chinese Herbal Medicine 2014 45(5):659-664. 2. Cheng Jian, Di Liuqing, Shan Jinjun, Zhao Xiaoli, Kang 'an, Bi Xiaolin, Li Junsong. Effect of Achyranthes bidentata on the pharmacokinetics of chlorogenic acid, isoglycyrrhizin, harbaogerin and glycyrrhizin in Tongsaimai pellets [J]. Chinese Journal of Traditional Chinese Medicine, 2014,39(08):1502-1508. 3. Zhou Bingwen, Zhong Xiaoming, Huang Zhen. Optimization of Hot Reflux Extraction Process of Scrophulariae Cycloidoid Glycosides [J]. Chinese Patent Medicine, 2018, 040(006):1292-1297. 4. Li Li Zhou Xiaojiang Yuan Zhiying et al. Effects of Different Planting Methods on Yield and Quality of Scrophulariae [J]. Shi Zhen Guo Yi Guo Yao 2020 v.31;No.293(01):195-197. 5. Shen Zhanyun Zhu Bo Zhang Quanlong et al. Isolation and Identification of Endophytic Fungi Producing Haberoside and Haberosin Scrophulariae [J]. Chinese Journal of Traditional Chinese Medicine 2019 v.44(10):88-92. 6. Liu Fang, Huang Xiaojie, Lin Meiyu, et al. Study on Grade Quality of Scrophulariae [J]. New Chinese Medicine and Clinical Pharmacology, 202031 Volume 8, 978-983 pages, ISTIC PKU CSCD CA, 2020. 7. Liu Fang, Zhou Xiaojiang, Yuan Zhiying, et al. Study on Grade Quality of Scrophulariae Radix Based on Fingerprint Combined with Multi-index Determination [J]. Chinese Herbal Medicine, 2019, 50(05):1238-1243. 8. He Shiru, Li Li, Xu Guangming, such as. Solid Phase Extraction High Performance Liquid Chromatography for Rapid Determination of Active Components in Scrophulariae [J]. Asia Pacific Traditional Medicine, 2020, 016(001):54-57. 9. Li Li Zhou Xiaojiang Yuan Zhiying et al. Dispersive Solid Phase Extraction HPLC Determination of Five Indicator Components in Scrophulariae [J]. Straits Pharmaceutical 2019 031(011):30-33. 10. Zhu Xiaofu, Deng Caifu, Tan Qiusheng, yang Dan, Lu Sheng'e, Ren Fengming. Quality Evaluation of Different "Sweating" Days of Scrophulariae Produced in Chongqing [J]. Traditional Chinese Medicine and Clinic, 2020,11(05):8-10. 11. [IF = 3.69] Qian Zhang et al."Qishen Granule alleviates endoplasmic Ethnopharmacol reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia." J. 2020 Apr;252:112573 |
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