| Molecular Formula | C11H22O5 |
| Molar Mass | 234.29 |
| Density | 1.046±0.06 g/cm3(Predicted) |
| Boling Point | 321.8±22.0 °C(Predicted) |
| pKa | 14.36±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Physical and Chemical Properties | Bioactive Hydroxy-PEG2-(CH2)2-Boc is an ADC linker used to synthesize antibody-coupled drugs (ADC). Hydroxy-PEG2-(CH2)2-Boc is derived from patented WO2004008101A2 (compound 196). Hydroxy-PEG2-(CH2)2-Boc can also be used as PROTAC linker for PROTAC synthesis.. |
| Downstream Products | Azido-PEG2-acid |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.268 ml | 21.341 ml | 42.682 ml |
| 5 mM | 0.854 ml | 4.268 ml | 8.536 ml |
| 10 mM | 0.427 ml | 2.134 ml | 4.268 ml |
| 5 mM | 0.085 ml | 0.427 ml | 0.854 ml |
Target
Non-cleavable
PEGs
Alkyl/ether
in vitro studies
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.