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L-Quebrachitol

L-Quebrachitol

CAS: 642-38-6

Molecular Formula: C7H14O6

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L-Quebrachitol - Names and Identifiers

Name L-Quebrachitol
Synonyms QUEBRACHITOL
L-QUEBRACHITOL
L-Quebrachitol
(-)-QUEBRACHITOL
3-O-METHYL-L-CHIRO-INOSITOL
2-O-METHYL-L-CHIRO-INOSITOL
1L-2-O-METHYL-CHIRO-INOSITOL
L-CHIRO-INOSITOL 2-METHYL ETHER
CAS 642-38-6

L-Quebrachitol - Physico-chemical Properties

Molecular FormulaC7H14O6
Molar Mass194.18
Density1.56±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point190-198 °C
Boling Point250.62°C (rough estimate)
Specific Rotation(α)(H2O)-80.3
Solubility DMSO : 250 mg/mL (1287.47 mM; Need ultrasonic)
AppearanceSolid
ColorWhite to Off-White
pKa12.98±0.70(Predicted)
Storage ConditionSealed in dry,2-8°C
Refractive Index1.572
MDLMFCD00021405
Physical and Chemical PropertiesChemical properties of white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from seabuckthorn.
UseUses for content determination/identification/pharmacological experiments and other pharmacological effects: antioxidant, anti-aging, cholesterol reduction

L-Quebrachitol - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS24/25 - Avoid contact with skin and eyes.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

L-Quebrachitol - Reference Information

introduction (-)-white sparrow lignin is a white crystalline powder, which has the effects of anti-oxidation, delaying aging and lowering cholesterol.
biological activity L-Quebrachitol (L-QCT) is a natural product that can be isolated from many plants and promotes proliferation and cell DNA synthesis. L-Quebrachitol can up-regulate bone morphogenetic protein-2 (BMP-2), runt-related transcription factor-2 (Runx2) and mitogen-activated protein kinase (MAPK) related regulatory genes and Wnt/β-catenin signaling pathway, and down-regulate mRNA levels of nuclear factor-κB(NF-κB) ligand (RANKL) receptor activator.
target TargetValue BMP-2 () Runx2 () MAPK () Wnt/β-catenin () NF-κB ()
TargetValue
chemical properties white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from seabuckthorn.
use (-)-white sparrow lignin has the effects of anti-oxidation, anti-aging and cholesterol reduction.
used for content determination/identification/pharmacological experiments and other pharmacological effects: anti-oxidation, anti-aging, lower cholesterol
Last Update:2024-04-09 19:05:03

L-Quebrachitol - Uses and synthesis methods

Introduction

(-)-white sparrow lignin is a white crystalline powder, which has the effects of anti-oxidation, delaying aging and lowering cholesterol.

biological activity

L-Quebrachitol (L-QCT) is a natural product that can be isolated from many plants and promotes proliferation and cell DNA synthesis. L-Quebrachitol can up-regulate bone morphogenetic protein-2 (BMP-2), runt-related transcription factor-2 (Runx2) and mitogen-activated protein kinase (MAPK) related regulatory genes and Wnt/β-catenin signaling pathway, and down-regulate nuclear factor-& kappa;B(NF-& kappa;B) mRNA level of ligand (RANKL) receptor activator.

Target

Target Value

BMP-2

Runx2

MAPK

Wnt/β-catenin

NF-κ B

Last Update:2024-04-09 01:59:51
L-Quebrachitol
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: (-)-Quebrachitol Visit Supplier Webpage Request for quotation
CAS: 642-38-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: (1R,2S,3S,4S,5R,6R)-6-Methoxycyclohexane-1,2,3,4,5-pentaol Request for quotation
CAS: 642-38-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: L-Quebrachitol Visit Supplier Webpage Request for quotation
CAS: 642-38-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: L-Quebrachitol (Standard) Visit Supplier Webpage Request for quotation
CAS: 642-38-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: L-Quebrachitol Visit Supplier Webpage Request for quotation
CAS: 642-38-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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L-Quebrachitol
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