LDK378
LDK378
CAS: 1032900-25-6
Molecular Formula: C28H36ClN5O3S
LDK378 - Names and Identifiers
LDK378 - Physico-chemical Properties
| Molecular Formula | C28H36ClN5O3S |
| Molar Mass | 558.14 |
| Density | 1.251±0.06 g/cm3(Predicted) |
| Melting Point | 173-175°C |
| Boling Point | 720.7±70.0 °C(Predicted) |
| Solubility | DMSO 20 mg/mL heat Water <1 mg/mL Ethanol 3 mg/mL |
| Appearance | Off-white solid. |
| Color | White to Off-White |
| pKa | 10.16±0.10(Predicted) |
| Storage Condition | -20°C Freezer |
| MDL | MFCD26142648 |
LDK378 - Introduction
LDK378 is a potent ALK inhibitor with an IC50 of 0.2 nM, acting on IGF-1R and InsR with a selectivity of 40 and 35 times, respectively.
Last Update：2022-10-16 17:11:39
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