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Larotaxel

Larotaxel

CAS: 156294-36-9

Molecular Formula: C45H53NO14

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Larotaxel - Names and Identifiers

Name Larotaxel
Synonyms XRP9881
Larotaxel
PNU 100940
Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (1S,2S,4S,7R,8aR,9aS,10aR,12aS,12bR)-7,12a-bis(acetyloxy)-1-(benzoyloxy)-1,3,4,7,8,9,9a,10,10a,12,12a,12b-dodecahydro-2-hydroxy-5,13,13-trimethyl-8-oxo-2,6-methano-2H-cyclodeca[3,4]cyclopropa[4,5]benz[1,2-b]oxet-4-yl ester
CAS 156294-36-9

Larotaxel - Physico-chemical Properties

Molecular FormulaC45H53NO14
Molar Mass831.9
Density1.37
Melting Point170 - 174°C (dec.)
Boling Point889.3±65.0 °C(Predicted)
Solubility Soluble in DMSO, insoluble in water
AppearanceForm Solid, color White to Off-White
pKa11.20±0.46(Predicted)
Storage Condition-20°C Freezer
MDLMFCD00925691
Physical and Chemical PropertiesBioactive Larotaxel (XRP9881) is a taxane analog with pre-clinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, and finally leads to cell death through apoptosis. Larotaxel (XRP9881) has the ability to cross the blood-brain barrier and has much lower affinity for P-glycoprotein 1 than Docetaxel.
UseIntroduction Lailontaisin is a kind of purple alkyl analog with more novel skeleton structure. The results of biological research show that its in vitro anti-cancer activity is significantly better than that of paclitaxel and docetaxel, and the results of its in vivo activity research are also exciting. In the second phase of clinical research, people are very satisfied with the significant anti-cancer effect and low side effects of leontazine, especially for ovarian cancer and breast cancer that overexpress multidrug resistance genes.

Larotaxel - Nature

Solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Last Update:2024-04-10 22:29:15
Larotaxel
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Wuhan Boye Science And Technology Development Co., Ltd.
Featured Products
Product Name: Larotaxel Request for quotation
CAS: 156294-36-9
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Larotaxel Request for quotation
CAS: 156294-36-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Larotaxel Visit Supplier Webpage Request for quotation
CAS: 156294-36-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Larotaxel Visit Supplier Webpage Request for quotation
CAS: 156294-36-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Spot supply
Product Name: XRP9881 Visit Supplier Webpage Request for quotation
CAS: 156294-36-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
Spot supply
Product Name: Larotaxel Visit Supplier Webpage Request for quotation
CAS: 156294-36-9
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Larotaxel Visit Supplier Webpage Request for quotation
CAS: 156294-36-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Larotaxel
1126032-65-2
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GS-17792
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