LevistilideA
LevistilideA
CAS: 88182-33-6
Molecular Formula: C24H28O4
LevistilideA - Names and Identifiers
| Name | LevistilideA |
| Synonyms | LevistilideA Levistolid A Levistolide A Diligustilide Levistilide A Z,Z'-6,6',7,3'a-Diligustilide |
| CAS | 88182-33-6 |
LevistilideA - Physico-chemical Properties
| Molecular Formula | C24H28O4 |
| Molar Mass | 380.48 |
| Density | 1.23 |
| Melting Point | 112-114 °C |
| Boling Point | 623.8±55.0 °C(Predicted) |
| Solubility | Easily soluble in non-polar solvents such as petroleum ether and chloroform. |
| Appearance | Colorless needle crystal |
| Storage Condition | 2-8°C |
| Physical and Chemical Properties | White crystal, soluble in methanol, ethanol, ethyl acetate, chloroform, derived from the root of Umbelliferae plant Ligusticum wallichii Rhizoma Chuanxiong. |
LevistilideA - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29322090 |
LevistilideA - Reference
| Reference Show more | 1. Yan Menglin, Ding Guoyu, Cong Longfei, et al. Rapid near-infrared evaluation of Angelica sinensis vasodilation efficacy based on quality markers [J]. Chinese herbal medicine, 2019, v.50;No.654(19):27-35. 2. Wang Zhenheng, Wang Yinquan, Fan Qin, et al. Effects of ultraviolet-B radiation on phthalide content in angelica sinensis [J]. Journal of Gansu University of Chinese Medicine, 2019(6). 3. Feng Xue, Gao Yuqiao, fan Qiongying, Su Junhua, Zhao Baohua. Simultaneous determination of four effective components in Jingfang Baidu oral liquid by LC-ESI/MS [J]. Journal of Pharmaceutical Analysis, 2017,37(08):1489-1496. 4. Liu Ming, Wang Huisen, Li Shen. Study on quality standard of Chunhua Jiangya tablets [J]. Northwest Pharmaceutical Journal, 2020, v.35(03):9-12. 5. Yan Shunan, Wang Yinquan, Ma Lili, et al. Optimization of balanced dehydration drying process of Angelica sinensis [J]. Chinese traditional medicines, 2020, v.42(03):135-142. 6. Peng Tong, Wang Yinquan, Zhang Yali, Yan Shunan, Qin Jun, Ma Qin state. Comparison of 8 effective components between Angelica sinensis of Linqu and Minxian County [J]. Journal of Gansu University of Chinese Medicine, 2020,37(06):29-33. 7. Yan Menglin, Cong Longfei, Zhang Ziyan, Jiang Min, Xie Lei, Baigang. Rapid Evaluation of Anti-inflammatory efficacy of Angelica sinensis by near infrared spectroscopy based on quality markers [J]. Journal of analysis and testing, 2020,39(11):1320-1326. 8. Zhang, natiing, et al. "Pharmacokinetics-based identification of potential therapeutic phthalides from XueBiJing, a Chinese herbal injection used in sepsis management." Drug Metabolism and Disposition 46.6 (2018): 823-834.DOI: https://doi.org/10.1124/dmd.11 9. [IF=3.935] Zhengchao Ji et al."Global identification and quantitative analysis of representative components of Xin-Nao-Kang Capsule, a traditional Chinese medicinal formula, by UHPLC-Q-TOF-MS and UHPLC-TQ-MS."J Pharmaceut Biomed. 2021 May;198:114002 |
LevistilideA - Reference Information
| biological activity | Levistolide A is a natural compound isolated from the traditional Chinese medicine Chuanxiong, used to study cancer. Levistolide A can induce apoptosis through ROS-mediated endoplasmic reticulum stress. |
| chemical properties | white crystal, soluble in methanol, ethanol, ethyl acetate, chloroform, derived from the root of Umbelliferae plant Ligusticum wallichii Rhizoma Chuanxiong. |
| use | ocelinolide a can inhibit rhythmic uterine contractions and can be used to treat liver fibrosis or cirrhosis. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: promoting blood circulation and promoting qi, dispelling wind and relieving pain. |
Last Update：2024-04-09 21:54:55
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