MM
Hexamethyldisiloxane
CAS: 107-46-0
Molecular Formula: C6H18OSi2
MM - Names and Identifiers
| Name | Hexamethyldisiloxane |
| Synonyms | MM os10 HMDO HMDSO sws-f221 SILICONE FLUID Hexamethyldisiloxane Hexamethyl Disiloxane oxybis(trimethyl-silan Oxybis(trimethylsilane) Silane, oxybis(trimethyl)- 2,2,4,4-TETRAMETHYL-3-OXA-2,4-DISILAPENTANE |
| CAS | 107-46-0 |
| EINECS | 203-492-7 |
| InChI | InChI=1/C6H18OSi2/c1-8(2,3)7-9(4,5)6/h1-6H3 |
| InChIKey | UQEAIHBTYFGYIE-UHFFFAOYSA-N |
MM - Physico-chemical Properties
| Molecular Formula | C6H18OSi2 |
| Molar Mass | 162.38 |
| Density | 0.764g/mLat 20°C(lit.) |
| Melting Point | −59°C(lit.) |
| Boling Point | 101°C(lit.) |
| Flash Point | 33°F |
| Water Solubility | insoluble |
| Solubility | 0.00037g/l insoluble |
| Vapor Presure | 20 hPa (20 °C) |
| Vapor Density | >1 (vs air) |
| Appearance | liquid |
| Specific Gravity | 0.76 |
| Color | Colorless to Almost colorless |
| BRN | 1736258 |
| Storage Condition | Store below +30°C. |
| Stability | Stable, but moisture sensitive. Highly flammable. Incompatible with strong acids, strong bases, oxidizing agents. |
| Sensitive | 1: no significant reaction with aqueous systems |
| Explosive Limit | 0.5-21.8%(V) |
| Refractive Index | n20/D 1.377(lit.) |
| Physical and Chemical Properties | Character: colorless transparent liquid. boiling point 99.5 ℃ relative density 0.7606 refractive index 1.3750 flash point -1.1 ℃ solubility insoluble in water, soluble in a variety of organic solvents. |
| Use | As a head agent, cleaning agent, release agent, mainly used in organic chemical and pharmaceutical chemical production. It is used as a head-sealing agent in the production of silicone oil, and can also be used as a raw material of silazane. For silicone rubber, drugs, gas chromatography stationary liquid, Analytical reagents, hydrophobic agent, etc. |
MM - Risk and Safety
| Risk Codes | R11 - Highly Flammable R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R65 - Harmful: May cause lung damage if swallowed R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R48/23/24/25 - R36/38 - Irritating to eyes and skin. R46 - May cause heritable genetic damage R45 - May cause cancer |
| Safety Description | S16 - Keep away from sources of ignition. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S53 - Avoid exposure - obtain special instructions before use. |
| UN IDs | UN 1993 3/PG 2 |
| WGK Germany | 3 |
| RTECS | JM9237000 |
| FLUKA BRAND F CODES | 10 |
| TSCA | Yes |
| HS Code | 29310095 |
| Hazard Class | 3 |
| Packing Group | II |
| Toxicity | LD50 orally in Rabbit: > 12160 mg/kg LD50 dermal Rat > 2000 mg/kg |
MM - Upstream Downstream Industry
| Raw Materials | Chlorotrimethylsilane |
MM - Nature
Open Data Verified Data
colorless transparent liquid. The relative density was 0. 7606. Boiling point 99.5 °c. Flash point -1.1 °c. Refractive index 3750. Insoluble in water, soluble in a variety of organic solvents. Easy deliquescence, flammable, in case of high heat, open flame, strong oxidant, there is the risk of causing combustion.
Last Update：2025-06-10 22:55:16
MM - Preparation Method
Open Data Verified Data
trimethylchlorosilane was hydrolyzed in water, washed with water and subjected to rectification.
Last Update：2022-01-01 10:54:23
MM - Application
Open Data Verified Data
important silicone oil and silicone resin intermediates, pharmaceutical raw materials, chemical reagents (used as gas chromatography stationary liquid).
Last Update：2025-08-19 16:24:40
MM - Safety
Open Data Verified Data
60kg galvanized iron drum or 0.5kg brown glass bottle packaging. The words "flammable articles" shall be clearly indicated. Risk code: 61176. Temperature <30 ℃. Keep away from fire and heat source, and store in the dark. The packaging should be sealed. Light loading and light unloading during handling to prevent package breakage.
Last Update：2025-06-10 22:55:16
MM - Reference Information
| LogP | 5.06 at 20℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | hexamethyldisiloxane (silicone ether, MM head agent), colorless transparent liquid, easy deliquescence. Insoluble in water, soluble in a variety of organic solvents. Used as silicone oil, silicone rubber, drugs, gas chromatography stationary liquid, analytical reagent, hydrophobic agent, etc. Prepared by hydrolysis of trimethylchlorosilane. |
| physical properties | hexamethyldisiloxane is a colorless transparent liquid. Easy deliquescence, flammable, in case of high heat, open flame, strong oxidant, there is the risk of causing combustion. Boiling point 99.5 °c. Flash point -1.1 °c. Relative density (d2525)0.7606. Refractive index 1.3750. Insoluble in water, soluble in a variety of organic solvents. |
| Application | hexamethyldisiloxane is an important primary raw material of organic silicon, it is often used as a capping agent for silicone silicone oil production, or for silicone rubber, drugs, gas chromatography, Analytical reagents, hydrophobic agents and medical electronic components and other cleaning agents. Hexamethyldisiloxane molecular chain structure of the Si-O-Si bond with high chemical bond energy (460. 5 kJ /mol), The polysiloxane prepared by using it as a head agent has good thermal stability and chemical stability. |
| preparation | hexamethyldisiloxane was synthesized by hydrolysis of chlorotrimethylsilane, water and sodium hydroxide as raw materials: add a certain amount of water in a 500ml three-necked flask, control the reaction temperature in a water bath, adjust the magnetic stirrer to a certain speed, then slowly add 50ml of trimethylchlorosilane with a syringe, and take out the reaction solution after a certain reaction time, after cooling, washing, separation and distillation under reduced pressure, the refined hexamethyldisilazane was finally obtained. The composition and purity of the product were analyzed by gas chromatography-mass spectrometry, and the yield was calculated. The optimal process conditions were as follows: adding 0.4mol of sodium hydroxide solid, the reaction temperature was 25 ℃, the reaction time was 30min, the volume ratio of water: trimethylchlorosilane was 1:1. The yield of hexamethyldisilazane was up to 99.95% and the purity was up to 99.876%. |
| Use | as a headstock agent, cleaning agent, and release agent, mainly used in organic chemical and pharmaceutical production used as a hydrophobic agent, insulating material and moisture-proof agent used in the circulation of cooling liquid and the manufacture of various types of organic silicon products, also as hydrophobic agent, used for fiber fabric surface treatment, insulation and moisture resistance of radio parts. It is also used as a stationary liquid for gas chromatography. This product is mainly used in the production of organic chemical and pharmaceutical chemical industry as a head sealing agent, cleaning agent and stripping agent. as a head sealing agent, cleaning agent, stripping agent, mainly used in organic chemical and pharmaceutical chemical production. It is used as a head-sealing agent in the production of silicone oil, and can also be used as a raw material of silazane. For silicone rubber, drugs, gas chromatography stationary liquid, Analytical reagents, hydrophobic agent, etc. |
| production method | 62.49g(0.575mol) of chlorotrimethylsilane was added dropwise to 72.7g(0.06mol) of N, A solution of N-dimethylaniline and 7g of water was heated at reflux for 1H. After atmospheric distillation, the 98-101 ° C. Fraction was collected and dried to give 43-44g of hexamethyldisilyl ether in a yield of 92-94%. Industrial production is the hydrolysis of chlorotrimethylsilane at 30-40 °c. |
| category | flammable liquid |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LDL0: 8 mL/kg; Peritoneal-mouse LD50: 4500 mg/kg |
| stimulation data | Skin-rabbit 500 mg/24 h mild |
| flammability hazard characteristics | in case of open flame, high temperature, flammable oxidant; Combustion stimulus smoke |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Stored separately from oxidants and acids |
| extinguishing agent | dry powder, dry sand, carbon dioxide, foam |
| spontaneous combustion temperature | 340°C |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 15:16:45
Supplier List
Featured ProductsSpot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Featured ProductsSpot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: +86-0512-58980899；+86-0512-58228762
Email: sales@zjgxinyachem.com
sales@zjgltchem.com
Mobile: +86-13915696858
QQ: 42516274
Wechat: 13915696858
WhatsApp: 86 13915696858
Spot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Product Name: Hexamethyldisiloxane Request for quotation
CAS: 107-46-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 107-46-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Hexamethyldisiloxane(HMDSO) Visit Supplier Webpage Request for quotationCAS: 107-46-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Hexamethyldisiloxane Visit Supplier Webpage Request for quotationCAS: 107-46-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Hexamethyldisiloxane Visit Supplier Webpage Request for quotationCAS: 107-46-0
Tel: +86-531-82316028
Email: sales@zsscm.com.cn
Mobile: +8615726167122
Product Name: Hexamethyldisiloxane Request for quotation
CAS: 107-46-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
CAS: 107-46-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
Featured ProductsSpot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Featured ProductsSpot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: +86-0512-58980899；+86-0512-58228762
Email: sales@zjgxinyachem.com
sales@zjgltchem.com
Mobile: +86-13915696858
QQ: 42516274
Wechat: 13915696858
WhatsApp: 86 13915696858
Spot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Hexamethyldisiloxane Request for quotationCAS: 107-46-0
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Product Name: Hexamethyldisiloxane Request for quotation
CAS: 107-46-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
CAS: 107-46-0
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Hexamethyldisiloxane(HMDSO) Visit Supplier Webpage Request for quotationCAS: 107-46-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Hexamethyldisiloxane Visit Supplier Webpage Request for quotationCAS: 107-46-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Hexamethyldisiloxane Visit Supplier Webpage Request for quotationCAS: 107-46-0
Tel: +86-531-82316028
Email: sales@zsscm.com.cn
Mobile: +8615726167122
Product Name: Hexamethyldisiloxane Request for quotation
CAS: 107-46-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
CAS: 107-46-0
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
View History
Raw Materials for MM