MX69
MX69
CAS: 1005264-47-0
Molecular Formula: C27H26N2O4S
MX69 - Names and Identifiers
| Name | MX69 |
| Synonyms | MX69 MX-69 CS-2402 MX69 (MX 69 Benzoic acid, 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]- |
| CAS | 1005264-47-0 |
MX69 - Physico-chemical Properties
| Molecular Formula | C27H26N2O4S |
| Molar Mass | 474.57 |
| Solubility | DMSO: ≥ 30 mg/mL |
| Storage Condition | -20℃ |
| In vitro study | MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro. |
| In vivo study | MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo. |
MX69 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.107 ml | 10.536 ml | 21.072 ml |
| 5 mM | 0.421 ml | 2.107 ml | 4.214 ml |
| 10 mM | 0.211 ml | 1.054 ml | 2.107 ml |
| 5 mM | 0.042 ml | 0.211 ml | 0.421 ml |
Last Update：2024-01-02 23:10:35
MX69 - Reference Information
| biological activity | MX69 is an MDM2/XIAP inhibitor, commonly used in anti-cancer research. |
| in vitro study | MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animalmodels. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro. |
| in vivo study | MX69-induced MDM2 downregulation results in activation of p53 which contributes to inhibition of cancer cell proliferation in vivo. |
Last Update：2024-04-09 20:49:11
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Product Name: MX69 Visit Supplier Webpage Request for quotationCAS: 1005264-47-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: MX69 Request for quotationCAS: 1005264-47-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Multiple SpecificationsSpot supply
Product Name: MX69 (Standard) Visit Supplier Webpage Request for quotationCAS: 1005264-47-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: MX69 Visit Supplier Webpage Request for quotationCAS: 1005264-47-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: MX69 Visit Supplier Webpage Request for quotationCAS: 1005264-47-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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