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Motolimod

Motolimod

CAS: 926927-61-9

Molecular Formula: C28H34N4O2

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Motolimod - Names and Identifiers

Name Motolimod
Synonyms VTX2337
VTX-378
VTX 378
VTX 2337
VTX-2337
MOTOLIMOD
Motolimod
Obicetrapib
Motolimod(VTX-2337)
2-amino-n,n-dipropyl-8-[4-(pyrrolidine-1-carbonyl)phenyl]-3h-1-benzazepine-4-carboxamide
2-amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide
CAS 926927-61-9

Motolimod - Physico-chemical Properties

Molecular FormulaC28H34N4O2
Molar Mass458.6
Density1.19±0.1 g/cm3(Predicted)
Boling Point718.7±70.0 °C(Predicted)
Solubility 10 mM in DMSO
Appearancesolid
ColorOff-white or pale yellow
pKa2.47±0.40(Predicted)
Storage Condition-20°C
StabilityStable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
In vitro studyVTX-2337 stimulated the production of TNFα and IL-12 In PBMCs with EC50 of 140 nM and 120 nM, respectively. In monocytes and mDCs, VTX-2337 selectively induced TNFα and IL-12 production by NF-κB activation. VTX-2337 also stimulates IFNγ production in NK cells, increases cytolysin function in myogenic NK cells, and enhances ADCC.
In vivo studyIn a mouse model of ovarian cancer, TX-2337 enhances the effect of liposomal doxorubicin (PLD).

Motolimod - Preparation solution concentration reference

 1mg5mg10mg
1 mM2.181 ml10.903 ml21.806 ml
5 mM0.436 ml2.181 ml4.361 ml
10 mM0.218 ml1.09 ml2.181 ml
5 mM0.044 ml0.218 ml0.436 ml
Last Update:2024-01-02 23:10:35
Motolimod
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Shanghai Amole Biotechnology Co., Ltd.
Featured ProductsSpot supply
Product Name: Motolimod Request for quotation
CAS: 926927-61-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Motolimod (VTX-2337) Visit Supplier Webpage Request for quotation
CAS: 926927-61-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Motolimod Visit Supplier Webpage Request for quotation
CAS: 926927-61-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: VTX-2337; VTX-378 Visit Supplier Webpage Request for quotation
CAS: 926927-61-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
BOC Sciences
Spot supply
Product Name: Motolimod Visit Supplier Webpage Request for quotation
CAS: 926927-61-9
Tel: +16314854226
Email: info@bocsci.com
Mobile: +16314854226
Linkedin: https://www.linkedin.com/company/boc-sciences
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Motolimod Visit Supplier Webpage Request for quotation
CAS: 926927-61-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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Motolimod
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