N-(2,3-Dimethyl-6-nitrophenyl)acetamide

N-(2,3-Dimethyl-6-nitrophenyl)acetamide - Names and Identifiers

Name	N-(2,3-Dimethyl-6-nitrophenyl)acetamide
Synonyms	2,3-Dimethyl-6-nitroacetanilide 2',3'-Dimethyl-6'-nitroacetanilide N-(2,3-DiMethyl-6-nitrophenyl)acetaMide N-(2,3-Dimethyl-6-nitrophenyl)acetamide Acetamide, N-(2,3-dimethyl-6-nitrophenyl)-
CAS	138330-47-9
InChI	InChI=1S/C10H12N2O3/c1-6-4-5-9(12(14)15)10(7(6)2)11-8(3)13/h4-5H,1-3H3,(H,11,13)

N-(2,3-Dimethyl-6-nitrophenyl)acetamide - Physico-chemical Properties

Molecular Formula	C10H12N2O3
Molar Mass	208.21

N-(2,3-Dimethyl-6-nitrophenyl)acetamide - Introduction

N-acetyl -2, 3-dimethyl-6-nitroaniline, chemical formula C10H12N2O3, is an organic compound. The following is a brief description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid
-melting point: 117-120 ℃
-Boiling point: 337 ℃
-Insoluble in water, soluble in organic solvents such as ether and alcohols
-has a strong corrosive, irritating effect on the skin, eyes and respiratory tract

Use:
-As an intermediate in organic synthesis, it is widely used in the fields of pharmaceuticals, dyes and pesticides
-Used as an intermediate for antibiotics and anti-inflammatory drugs in certain drugs

Preparation Method:
The preparation method of N-acetyl -2, 3-dimethyl-6-nitroaniline usually involves the following steps:
1.2,4-dinitroethylbenzene reacts with acetic anhydride to give 2,4-dinitroethyl acetic anhydride.
2.2,4-dinitroethyl acetic anhydride is reduced to give 2,4-dinitroethylbenzene.
3. reacting 2,4-dinitroethylbenzene with formic anhydride to obtain N-acetyl 2,4-dinitroethylbenzene.
4. Finally, N-acetyl 2,4-dinitroethylbenzene is reacted with methylamine to obtain N-acetyl-2, 3-dimethyl-6-nitroaniline.

Safety Information:
-The compound is highly corrosive and irritating. Contact with skin, eyes and respiratory tract should be avoided and personal protective equipment should be worn.
-in the use of the process to strictly abide by the chemical safety procedures, to avoid dust and volatiles.
-Waste disposal shall be carried out in accordance with local environmental regulations, and any form of large-scale discharge is prohibited.

Last Update：2024-04-09 21:00:56