N-(2-hydroxyethyl)-4-methylbenzenesulfonamide
N-(2-hydroxyethyl)-4-methylbenzenesulfonamide
CAS: 14316-14-4
Molecular Formula: C9H13NO3S
N-(2-hydroxyethyl)-4-methylbenzenesulfonamide - Names and Identifiers
| Name | N-(2-hydroxyethyl)-4-methylbenzenesulfonamide |
| Synonyms | N-(2-Hydroxyethyl)-4-toluenesulfonaMide N-(2-hydroxyethyl)-4-methylbenzenesulfonamide N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide Benzenesulfonamide, N-(2-hydroxyethyl)-4-methyl- |
| CAS | 14316-14-4 |
| InChI | InChI=1/C9H13NO3S/c1-8-2-4-9(5-3-8)14(12,13)10-6-7-11/h2-5,10-11H,6-7H2,1H3 |
N-(2-hydroxyethyl)-4-methylbenzenesulfonamide - Physico-chemical Properties
| Molecular Formula | C9H13NO3S |
| Molar Mass | 215.27 |
| Density | 1.263g/cm3 |
| Melting Point | 55-57°C |
| Boling Point | 380.2°C at 760 mmHg |
| Flash Point | 183.8°C |
| Solubility | Soluble in Dichloromethane and Methanol |
| Vapor Presure | 1.85E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White Waxy to Off-White |
| Storage Condition | Refrigerator |
| Refractive Index | 1.554 |
N-(2-hydroxyethyl)-4-methylbenzenesulfonamide - Introduction
N-(2-Hydroxyethyl) p-toluenesulfonamide, also known as p-toluenesulfonamido-2-hydroxyethyl ester, has the chemical formula C9H11NO4S. The following is a description of its nature, use, preparation and safety information:
Nature:
N-(2-Hydroxyethyl) p-toluenesulfonamide is a white crystalline solid with a high melting and boiling point. It is slightly soluble in water and soluble in many organic solvents such as alcohols and ethers.
Use:
N-(2-hydroxyethyl) p-toluenesulfonamide is mainly used as a reducing agent and catalyst in organic synthesis. It is commonly used in pharmaceutical and chemical research for the synthesis of compounds containing ester linkages and as a deprotection reagent for carboxylic acids.
Preparation Method:
N-(2-hydroxyethyl) p-toluenesulfonamide can be prepared by reacting p-toluenesulfonamide with ethylene glycol. The reaction is carried out at an appropriate temperature by introducing dry formaldehyde and ethylene glycol.
Safety Information:
N-(2-hydroxyethyl) p-toluenesulfonamide is generally safe under normal conditions of use, but the following points should be noted:
1. Avoid direct contact with skin and inhalation of dust or vapor during use, and wear personal protective equipment such as gloves, protective glasses and masks when using.
2. in use and storage, should be away from the fire and oxidant, to avoid fire and explosion.
3. If you accidentally touch or take it by mistake, rinse the affected area with water immediately, and seek medical assistance as soon as possible, and bring a chemical label.
4. Waste shall be disposed in accordance with local regulations and shall not be dumped or discharged at will.
Nature:
N-(2-Hydroxyethyl) p-toluenesulfonamide is a white crystalline solid with a high melting and boiling point. It is slightly soluble in water and soluble in many organic solvents such as alcohols and ethers.
Use:
N-(2-hydroxyethyl) p-toluenesulfonamide is mainly used as a reducing agent and catalyst in organic synthesis. It is commonly used in pharmaceutical and chemical research for the synthesis of compounds containing ester linkages and as a deprotection reagent for carboxylic acids.
Preparation Method:
N-(2-hydroxyethyl) p-toluenesulfonamide can be prepared by reacting p-toluenesulfonamide with ethylene glycol. The reaction is carried out at an appropriate temperature by introducing dry formaldehyde and ethylene glycol.
Safety Information:
N-(2-hydroxyethyl) p-toluenesulfonamide is generally safe under normal conditions of use, but the following points should be noted:
1. Avoid direct contact with skin and inhalation of dust or vapor during use, and wear personal protective equipment such as gloves, protective glasses and masks when using.
2. in use and storage, should be away from the fire and oxidant, to avoid fire and explosion.
3. If you accidentally touch or take it by mistake, rinse the affected area with water immediately, and seek medical assistance as soon as possible, and bring a chemical label.
4. Waste shall be disposed in accordance with local regulations and shall not be dumped or discharged at will.
Last Update：2024-04-10 22:29:15
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View History
N-(2-hydroxyethyl)-4-methylbenzenesulfonamide
6-Bromo-2-Indolecarboxylic Ethyl Ester
3-(CARBOXYMETHYL)-2-(2-PENTENYL)CYCLOPENTANONE
6-Bromo-2-Indolecarboxylic Ethyl Ester
3-(CARBOXYMETHYL)-2-(2-PENTENYL)CYCLOPENTANONE