N-(3-aminophenyl)acrylamide
N-(3-aminophenyl)acrylamide
CAS: 16230-24-3
Molecular Formula: C9H10N2O
N-(3-aminophenyl)acrylamide - Names and Identifiers
| Name | N-(3-aminophenyl)acrylamide |
| Synonyms | N-(3-aminophenyl)acrylamide N-(3-aminophenyl)prop-2-enamide N-(3-Aminophenyl)-2-propenamide 2-Propenamide, N-(3-aminophenyl)- |
| CAS | 16230-24-3 |
N-(3-aminophenyl)acrylamide - Physico-chemical Properties
| Molecular Formula | C9H10N2O |
| Molar Mass | 162.19 |
| Density | 1.189±0.06 g/cm3(Predicted) |
| Boling Point | 389.6±34.0 °C(Predicted) |
| pKa | 13.34±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Use | Uses N-(3-aminophenyl) acrylamide can be used in organic synthesis, pharmaceutical intermediates, etc. |
N-(3-aminophenyl)acrylamide - Introduction
N-(3-aminophenyl)acrylamide is an important organic compound with the chemical formula C10H11N3O. The following is an introduction to some properties, uses, methods and safety information about N-(3-aminophenyl)acrylamide:
Nature:
-Appearance: White crystalline or powdery solid.
-Melting point: about 160-165 degrees Celsius.
-Solubility: Can be dissolved in water, alcohol and ether solvents.
Use:
N-(3-aminophenyl)acrylamide has a wide range of applications in the chemical industry and scientific research:
-It can be used as an intermediate in organic synthesis and can be used to synthesize various functionalized organic compounds.
-In the field of polymers, it can be used to prepare polymer materials with special properties.
-In the field of biomedicine, it can be used as a component of a drug delivery system to control the release of drugs.
-It can be used as a modifier in chemical analysis and chromatographic separation.
Method:
N-(3-aminophenyl)acrylamide has many preparation methods, the most common methods are as follows:
1. Acetophenone and 3-aminobenzaldehyde are reacted to obtain N-(3-aminophenyl) acetone, and then the target product is obtained through amination reaction or amidation reaction.
2.3-amino benzoic acid and acrylic anhydride are reacted under alkaline conditions to generate N-(3-aminophenyl)acrylamide.
Safety Information:
N-(3-aminophenyl)acrylamide has low toxicity when used and handled correctly. However, the following safety measures should be followed:
-Avoid inhalation, ingestion or contact with skin, eyes, etc.
-Wear appropriate protective equipment such as lab gloves, goggles and lab clothes during operation.
-Operate in a well-ventilated place to avoid dust.
-Observe proper storage and handling practices and avoid contact with other chemicals and flammables.
For further information and recommendations on safe practices, please refer to the relevant Safety Data Sheet (SDS).
Nature:
-Appearance: White crystalline or powdery solid.
-Melting point: about 160-165 degrees Celsius.
-Solubility: Can be dissolved in water, alcohol and ether solvents.
Use:
N-(3-aminophenyl)acrylamide has a wide range of applications in the chemical industry and scientific research:
-It can be used as an intermediate in organic synthesis and can be used to synthesize various functionalized organic compounds.
-In the field of polymers, it can be used to prepare polymer materials with special properties.
-In the field of biomedicine, it can be used as a component of a drug delivery system to control the release of drugs.
-It can be used as a modifier in chemical analysis and chromatographic separation.
Method:
N-(3-aminophenyl)acrylamide has many preparation methods, the most common methods are as follows:
1. Acetophenone and 3-aminobenzaldehyde are reacted to obtain N-(3-aminophenyl) acetone, and then the target product is obtained through amination reaction or amidation reaction.
2.3-amino benzoic acid and acrylic anhydride are reacted under alkaline conditions to generate N-(3-aminophenyl)acrylamide.
Safety Information:
N-(3-aminophenyl)acrylamide has low toxicity when used and handled correctly. However, the following safety measures should be followed:
-Avoid inhalation, ingestion or contact with skin, eyes, etc.
-Wear appropriate protective equipment such as lab gloves, goggles and lab clothes during operation.
-Operate in a well-ventilated place to avoid dust.
-Observe proper storage and handling practices and avoid contact with other chemicals and flammables.
For further information and recommendations on safe practices, please refer to the relevant Safety Data Sheet (SDS).
Last Update：2024-04-09 20:13:35
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