N-Benzyloxycarbonyl-L-tyrosine
N-Benzyloxycarbonyl-L-tyrosine
CAS: 1164-16-5
Molecular Formula: C17H17NO5
N-Benzyloxycarbonyl-L-tyrosine - Names and Identifiers
| Name | N-Benzyloxycarbonyl-L-tyrosine |
| Synonyms | Z-TYR-OH Cbz-L-tyrosine CBZ-TYR-OH.H2O N-Cbz-L-tyrosine Z-Tyr-OH hydrate CBZ-L-Tyrosine-OH Z-L-tyrosine hydrate Z-L-tyrosine dihydrate CBZ-L-TYROSINE DIHYDRATE BenzyloxycarbonylLtyrosine N-cbz-L-tyrosine crystalline N-Benzyloxycarbonyl-L-tyrosine N-[(benzyloxy)carbonyl]tyrosine Na-Benzyloxycarbonyl-L-tyrosine N-Carbobenzyloxy-L-tyrosine dihydrate Z-L-TYROSINE extrapure for biochemistry N-Benzyloxycarbonyl-L-tyrosine~Z-Tyr-OH N-Carbobenzyloxy-L-tyrosine, Z-L-Tyrosine N-CBZ-L-Tyrosine N-Carbobenzyloxy-L-tyrosine 2-{[(Benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoic acid (2S)-2-{[(benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanoate (S)-2-(BENZYLOXYCARBONYLAMINO)-3-(4-HYDROXYPHENYL)PROPANOIC ACID DIHYDRATE |
| CAS | 1164-16-5 |
| EINECS | 214-609-6 |
| InChI | InChI=1/C17H17NO5/c19-14-8-6-12(7-9-14)10-15(16(20)21)18-17(22)23-11-13-4-2-1-3-5-13/h1-9,15,19H,10-11H2,(H,18,22)(H,20,21)/p-1/t15-/m0/s1 |
N-Benzyloxycarbonyl-L-tyrosine - Physico-chemical Properties
| Molecular Formula | C17H17NO5 |
| Molar Mass | 315.32 |
| Density | 1.1781 (rough estimate) |
| Melting Point | 57-60°C(lit.) |
| Boling Point | 454.88°C (rough estimate) |
| Flash Point | 299°C |
| Water Solubility | 1.53g/L(25 ºC) |
| Solubility | Acetic Acid (Sparingly), DMSO (Slightly), Methanol (Sparingly) |
| Vapor Presure | 7.21E-14mmHg at 25°C |
| Appearance | White to near white powder |
| Color | Off-White |
| BRN | 2169918 |
| pKa | 2.97±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 10.0 ° (C=1, AcOH) |
| MDL | MFCD00191899 |
N-Benzyloxycarbonyl-L-tyrosine - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Hazard Note | Irritant |
N-Benzyloxycarbonyl-L-tyrosine - Introduction
N-Benzyloxycarbonyl-L-tyrosine (N-benzyloxycarbonyl-L-tyrosine) is an organic compound. The following is an introduction to its properties, uses, preparation methods and safety information:
Properties: N-benzyloxycarbonyl-L-tyrosine is a white crystalline powder with the structural characteristics of phenoxycarbonyl and tyrosine. It dissolves well in organic solvents such as dimethylformamide (DMF) or dichloromethane (DCM).
Purpose: N-benzyloxycarbonyl-L-tyrosine is commonly used in organic synthesis reactions, especially as a protecting group in polypeptide synthesis. By introducing it into the tyrosine molecule, undesired reactions of tyrosine with other compounds during the reaction can be prevented.
Preparation method: N-benzyloxycarbonyl-L-tyrosine can be obtained by reacting tyrosine with N-benzyloxycarbonyl chloride. First, tyrosine is dissolved in a sodium alkaline solution, then N-benzyloxycarbonyl chloride is added, and the reaction is promoted by magnetic stirring during the reaction. Finally, the reaction mixture is neutralized with aqueous ammonia or hydrochloric acid to obtain N-benzyloxycarbonyl-L-tyrosine.
Safety Information: N-Benzyloxycarbonyl-L-tyrosine does not cause serious harm to humans and the environment under routine experimental conditions. However, as a chemical, it still needs to be handled properly. Care should be taken to avoid contact with skin, eyes and inhalation during use and storage. Wear appropriate personal protective equipment such as lab gloves, goggles, and lab coats. Proper handling and storage of organic compounds is an important measure to ensure safety.
Properties: N-benzyloxycarbonyl-L-tyrosine is a white crystalline powder with the structural characteristics of phenoxycarbonyl and tyrosine. It dissolves well in organic solvents such as dimethylformamide (DMF) or dichloromethane (DCM).
Purpose: N-benzyloxycarbonyl-L-tyrosine is commonly used in organic synthesis reactions, especially as a protecting group in polypeptide synthesis. By introducing it into the tyrosine molecule, undesired reactions of tyrosine with other compounds during the reaction can be prevented.
Preparation method: N-benzyloxycarbonyl-L-tyrosine can be obtained by reacting tyrosine with N-benzyloxycarbonyl chloride. First, tyrosine is dissolved in a sodium alkaline solution, then N-benzyloxycarbonyl chloride is added, and the reaction is promoted by magnetic stirring during the reaction. Finally, the reaction mixture is neutralized with aqueous ammonia or hydrochloric acid to obtain N-benzyloxycarbonyl-L-tyrosine.
Safety Information: N-Benzyloxycarbonyl-L-tyrosine does not cause serious harm to humans and the environment under routine experimental conditions. However, as a chemical, it still needs to be handled properly. Care should be taken to avoid contact with skin, eyes and inhalation during use and storage. Wear appropriate personal protective equipment such as lab gloves, goggles, and lab coats. Proper handling and storage of organic compounds is an important measure to ensure safety.
Last Update：2024-04-09 21:01:54
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