N-acetylglucosamine
N-acetyl-D-(+)-glucosamine
CAS: 7512-17-6;134451-94-8
Molecular Formula: C8H15NO6
N-acetylglucosamine - Names and Identifiers
N-acetylglucosamine - Physico-chemical Properties
| Molecular Formula | C8H15NO6 |
| Molar Mass | 221.21 |
| Density | 1.54 g/cm3 |
| Melting Point | 211 °C (dec.) (lit.) |
| Boling Point | 636.4±55.0 °C(Predicted) |
| Specific Rotation(α) | 42 º (c=2,water,2 hrs) |
| Flash Point | 338.7°C |
| Water Solubility | Soluble in concentrated hydrochloric acid, sulfuric acid, phosphoric acid and formic acid. Insoluble in water, dilute acids, dilute alkalis, concentrated alkalis and organic solvents. |
| Solubility | Soluble in water. |
| Vapor Presure | 8Pa at 20℃ |
| Appearance | White powder |
| Color | white to off-white |
| Merck | 14,4458 |
| BRN | 1727589 |
| pKa | 13.04±0.20(Predicted) |
| Storage Condition | -20°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | Hygroscopic |
| Refractive Index | 40.5 ° (C=1, H2O) |
| MDL | MFCD00061615 |
| Physical and Chemical Properties | Melting Point 201-204°C specific rotation 42 ° (c = 2,water,2 hrs) |
| Use | Used as a therapeutic agent for osteoarthritis, rheumatoid arthritis, food additives |
N-acetylglucosamine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust. |
| WGK Germany | 3 |
| RTECS | LZ6651000 |
| FLUKA BRAND F CODES | 3-10 |
| TSCA | Yes |
| HS Code | 29329985 |
| Hazard Note | Irritant |
N-acetylglucosamine - Reference
| Reference Show more | 1. [IF=6.953] Yan Zhou et al."Structural characterization and immunomodulatory activities of two polysaccharides from Rehmanniae Radix Praeparata."Int J Biol Macromol. 2021 Sep;186:385 2. [IF=2.629] Dai Yu-Lin et al."Low Molecular Weight Oligosaccharide from Panax ginseng C.A. Meyer against UV-Mediated Apoptosis and Inhibits Tyrosinase Activity In Vitro and In Vivo."Evid-Based Compl Alt. 2021;2021:8879836 3. [IF=3.167] Yuwei Liu et al."Structural characterization and immunomodulatory effects of extracellular polysaccharide from Lactobacillus paracasei VL8 obtained by gradient ethanol precipitation."JOURNAL OF FOOD SCIENCE. 2022 Apr 12 |
N-acetylglucosamine - Reference Information
| LogP | -2.2 at 23.7℃ |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | N-Acetylglucosamine (GlcNAc) is a monosaccharide that is normally passed through (1,4) the-β-linkage was subjected to linear polymerization. It may help in the treatment of autoimmune diseases. |
| Use | used as a therapeutic agent for osteoarthritis, rheumatoid arthritis, food additive An important precursor for the synthesis of bifid factor, in vivo has many important physiological functions; In the clinical treatment of rheumatic and rheumatoid arthritis drugs; As food antioxidants and food additives for infants, N-acetyl-D-glucosamine is a basic component of many important polysaccharides in biological cells, especially in the exoskeleton of crustaceans. It is an important precursor for the synthesis of bifid factor and has many important physiological functions in vivo. A derivatized glucose monomer found in polymers of bacterial cell walls, chitin, hyaluronic acid, and various glycans. D-GlcNAc was used to identify, distinguish and characterize N-acetyl-β-D-hexylaminases. |
Last Update：2024-04-09 21:32:08
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