Neomangiferin
Neomangiferin
CAS: 64809-67-2
Molecular Formula: C25H28O16
Neomangiferin - Names and Identifiers
| Name | Neomangiferin |
| Synonyms | eoMangiferin Neomangiferin Mangiferin 7-glucoside 9H-Xanthen-9-one,2-β-D-glucopyranosyl-7-(β-D-glucopyranosyloxy)-1,3,6-trihydroxy- 2-beta-d-glucopyranosyl-7-(b-d-glucopyranosyloxy)-1,3,6-trihydroxy-9h-xanthen-9-one |
| CAS | 64809-67-2 |
| InChI | InChI=1/C25H28O16/c26-4-12-17(31)20(34)22(36)24(39-12)14-8(29)3-11-15(19(14)33)16(30)6-1-10(7(28)2-9(6)38-11)40-25-23(37)21(35)18(32)13(5-27)41-25/h1-3,12-13,17-18,20-29,31-37H,4-5H2/t12-,13-,17-,18-,20+,21+,22-,23-,24+,25?/m1/s1 |
Neomangiferin - Physico-chemical Properties
| Molecular Formula | C25H28O16 |
| Molar Mass | 584.48 |
| Density | 1.839 |
| Melting Point | 220-221°C |
| Boling Point | 1026.4±65.0 °C(Predicted) |
| Solubility | Soluble in pyridine and 55% ethanol, slightly soluble in methanol and ethyl acetate, insoluble in ether, petroleum ether and chloroform. |
| Appearance | Pale yellow powder |
| pKa | 6.10±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.76 |
| MDL | MFCD04034741 |
| Physical and Chemical Properties | Light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from mango leaves, Anemarrhena. |
Neomangiferin - Risk and Safety
| HS Code | 29389090 |
Neomangiferin - Reference
| Reference Show more | 1. Peng Ping, Tian Ruihua, Du Jing, et al. Quality Characterization Analysis of single-and combined-Fried extracts from Baihu Guizhi decoction [J]. Chinese Journal of Traditional Chinese Medicine, 2018, 43(16). 2. Peng Ping, Wang Mengyu, Li Xiaoying, etc. Simultaneous determination of five effective index components in Baihu Guizhi decoction by HPLC [J]. World Science and Technology-modernization of traditional Chinese medicine, 2017(8):1391-1395. 3. Song zebi, Wu, Ying, Gao Hui. Determination of new Mangiferin, mangiferin and isomgiferin in Rhizoma anemarrhenae before and after salt processing by HPLC [J]. Modern medicine and clinic 2015 000(002):145-148. 4. Gao Yan, Zhang Shuang, Song zebi, etc. Study on the inhibitory effect of chemical constituents of salt anemarrhenae on α-glucosidase [J]. China medical science, 2016(21). 5. Li Fuxin, Yu Beibei, Sun Dandan, et al. Study on quality standard of white tiger decoction mixture [J]. Journal of Liaoning University of Traditional Chinese Medicine, 2018, 020(003):39-42. |
Neomangiferin - Reference Information
| action | new mangiferin is a class I innovative drug developed on the basis of extensive screening of single traditional Chinese medicine with basic research on diabetes application and separation and screening of active ingredients. Preclinical pharmacological studies have shown that neomangiferin has a certain effect on blood sugar, but more importantly, this product can reduce the content of sorbitol in red blood cells, sciatic nerve, lens and serum MDA, AGEs, and total cholesterol in diabetic rats. Levels, increase the activity of SOD and GSH-Px in serum, significantly reduce urinary albumin excretion, and increase creatinine clearance; reduce glomerular mesangial matrix accumulation and reduce renal pathological changes. |
| biological activity | Neomangiferin, a natural C- glucosyl xanthone, is separated from the rhizome of dry Anemarrhena asphodeloides. Neomangiferin can effectively reduce nonalcoholic fatty liver disease (NAFLD) induced by high-fat diet in rats. |
| chemical properties | light yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from mango leaves, anemarrhena. |
| use | neomangiferin has the effects of antioxidation and kidney injury protection. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: Mangiferin has many physiological activities and pharmacological effects such as anti-oxidation, anti-bacteria, anti-virus, immune regulation and anti-tumor. |
Last Update：2024-04-09 22:09:11
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