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Olmesartan

Olmesartan

CAS: 144689-78-1

Molecular Formula: C30H32N6O6

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Olmesartan - Names and Identifiers

Name Olmesartan
Synonyms Olmesartan
n-Butyl OlMesartan MedoxoMil
Olmesartan Medoxomil Impurity E
4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid
(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-butyl-4-(2-hydroxy-2-propanyl)-1-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-imidazole-5-carboxylate
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-(2-hydroxypropan-2-yl)-1H-imidazole-5-carboxylate
4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1h-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-CARBOXYLIC ACID (5-METHYL-2-OXO-1,3-DIOXOL-4-YL)METHYL ESTER
1H-Imidazole-5-carboxylic acid, 2-butyl-4-(1-hydroxy-1-methylethyl)-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
1H-IMIDAZOLE-5-CARBOXYLIC ACID, 4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-, (5-METHYL-2-OXO-1,3-DIOXOL-4-YL)METHYL ESTER
CAS 144689-78-1
InChI InChI=1S/C30H32N6O6/c1-5-6-11-24-31-26(30(3,4)39)25(28(37)40-17-23-18(2)41-29(38)42-23)36(24)16-19-12-14-20(15-13-19)21-9-7-8-10-22(21)27-32-34-35-33-27/h7-10,12-15,39H,5-6,11,16-17H2,1-4H3,(H,32,33,34,35)

Olmesartan - Physico-chemical Properties

Molecular FormulaC30H32N6O6
Molar Mass572.61
Density1.36
Boling Point808.7±75.0 °C(Predicted)
Flash Point442.916 °C
pKa4.15±0.10(Predicted)
Storage Condition-20℃
Physical and Chemical Properties

Olmesartan - Nature

Open Data Verified Data

white or pale yellow to white powder or crystalline powder. mp180 ~ 182 deg C (decomposition). Practically insoluble in water, insoluble in methanol.

Last Update:2025-06-10 22:55:16

Olmesartan - Preparation Method

Open Data Verified Data

potassium carbonate, dissolved in dimethylacetamide, is added dropwise with stirring at 60 °c, containing 4-(1-hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid (5-methyl -2-oxy -1.3-dioxole -4-yl) methyl Ester and 4-[2-(triphenylmethyltetrazol-5-yl) phenyl] benzyl bromide dimethyl acetamide solution, stirred reaction, after treatment, 4-(1-hydroxy-1-methylethyl)-2-propyl -1-[4-2-(triphenylmethyltetrazole-5-yl) phenyl] methylimidazole-5-carboxylic acid (5-methyl -2-oxy -1,3-= oxocyclopenten-4-yl) methyl ester. This was stirred with 75% aqueous acetic acid at 60 °c and treated to give olmesartan.

Last Update:2025-06-10 22:55:16

Olmesartan - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.746 ml8.732 ml17.464 ml
5 mM0.349 ml1.746 ml3.493 ml
10 mM0.175 ml0.873 ml1.746 ml
5 mM0.035 ml0.175 ml0.349 ml
Last Update:2024-01-02 23:10:35

Olmesartan - Application

Open Data Verified Data

It was developed by santhereby Pharma( Parsippany,NJ) Co. Ltd. It was approved for marketing in the United States by the U. S. Food and Drug Administration (FDA) in April 2002. An orally effective non-peptide angiotensin II receptor antagonist. Angiotensin converting enzyme II antagonist, used in the treatment of hypertension.

Last Update:2025-08-19 16:24:40
Olmesartan
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CAS: 144689-78-1
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Olmesartan Request for quotation
CAS: 144689-78-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Olmesartan Visit Supplier Webpage Request for quotation
CAS: 144689-78-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Olmesartan Visit Supplier Webpage Request for quotation
CAS: 144689-78-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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Olmesartan
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